머크SIP작용제
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머크SIP작용제 속성
- 끓는 점
- 565.9±60.0 °C(Predicted)
- 밀도
- 1.228±0.06 g/cm3(Predicted)
- 저장 조건
- Store at -20°C
- 용해도
- DMF: 5 mg/ml; DMF:PBS (pH 7.2) (1:10): 0.1 mg/ml; Ethanol: Partially soluble
- 물리적 상태
- 결정성 고체
- 산도 계수 (pKa)
- 2.66±0.20(Predicted)
안전
머크SIP작용제 C화학적 특성, 용도, 생산
개요
CAY10734 is an agonist of sphingosine-1-phosphate receptor 1 (S1P1; IC50 = 0.6 nM). It selectively binds S1P1 over S1P2, S1P3, and S1P4 receptors (IC50s = >10,000, 12,000, and 70 nM, respectively) but does also bind S1P5 receptors (IC50 = 1 nM) in radioligand binding assays. CAY10734 reduces the number of peripheral blood lymphocytes in mice, rats, and dogs, with the maximal response achieved when administered at doses of 10, 0.5, and 0.5 mg/kg, respectively. It increases graft survival in a rat skin allograft model when administered at a dose of 5 mg/kg per day in combination with cyclosporin A (CsA; ).머크SIP작용제 준비 용품 및 원자재
원자재
준비 용품
머크SIP작용제 공급 업체
글로벌( 23)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 |
799750417@qq.com | China | 8888 | 55 |
AdooQ BioScience, LLC | +1 (866) 930-6790 |
info@adooq.com | United States | 2784 | 58 |
BOC Sciences | 16314854226 |
info@bocsci.com | United States | 9926 | 65 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9707 | 58 |
Nanjing KaiMubo Pharmaceutical Co., Ltd. | 025-66162170 |
China | 7183 | 55 | |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 |
sales@glpbio.cn | China | 6870 | 58 |
Henan Alpha Chemical Co., Ltd. | 0371-0371-55055611 18137792234 |
3002694073@qq.com | China | 10245 | 58 |