베타-NADPH테트라소듐소금

베타-NADPH테트라소듐소금
베타-NADPH테트라소듐소금 구조식 이미지
카스 번호:
2646-71-1
한글명:
베타-NADPH테트라소듐소금
동의어(한글):
베타-NADPH테트라소듐소금
상품명:
Nadph tetrasodium salt
동의어(영문):
β-NADPH;NADPH (sodium salt);TPNH;TPNH,NA4;BETA-NADPH TETRASODIUM SALT;TRIPHOSPHOPYRIDINE NUCLEOTIDE (REDUCED) SODIUM SALT;TRIPHOSPHOPYRIDINE NUCLEOTIDE REDUCED TETRASODIUM SALT;TRIPHOSPHOPYRIDINE NUCLEOTIDE, REDUCED FORM TETRASODIUM SALT;BETA-NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE, REDUCED, 4NA;BETA-TRIPHOSPHOPYRIDINE NUCLEOTIDE TETRASODIUM SALT,REDUCED FORM
CBNumber:
CB7365362
분자식:
C21H31N7NaO17P3
포뮬러 무게:
769.42
MOL 파일:
2646-71-1.mol
MSDS 파일:
SDS

베타-NADPH테트라소듐소금 속성

녹는점
>250°C (dec.)
저장 조건
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
용해도
10mM NaOH: 용해성50mg/mL, 투명
물리적 상태
가루
색상
흰색에서 황백색까지
수용성
물에 용해됩니다(50mg/ml).
감도
Light Sensitive
Merck
14,6348
InChIKey
ZQJHSLJFGRIJQN-LRANKJFRNA-N
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi,F
위험 카페고리 넘버 36/37/38-11
안전지침서 26-36/37
WGK 독일 3
F 고인화성물질 3-10-23
HS 번호 29349990
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P271 옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.

베타-NADPH테트라소듐소금 C화학적 특성, 용도, 생산

개요

NADPH is the reduced form of the coenzyme NADP+; used in anabolic reactions such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.
NADPH, Tetrasodium Salt is a A ubiquitous coenzyme that acts as an electron donor in many reactions utilizing dehydrogenase and reductase enzymes. It is generated by reduction of the electron acceptor NADP+. The following biological pathways involve NADPH: formation of carbohydrate from CO2 during photosynthesis, maintenance of high levels of reduced glutathione in erythrocytes, reduction of thioredoxin.

화학적 성질

off-white to light yellow powder

용도

One of the biologically active forms of nicotinic acid. Differs from NAD by an additional phosphate group at the 2’position of the adenosine moiety. Serves as a coenzyme of hydrogenases and dehydroge nases. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions.

주요 응용

NADPH is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various biological reactions. In plants, NADPH is produced by ferredoxin-NADP+ reductase in the last step of the electron chain during photosynthesis. In animals is it predominantly produced by the pentose phosphate pathway, but is also generated by key mitochondrial enzymes. NADPH provides the reducing equivalents for biosynthetic reactions and the oxidation-reduction involved in protecting against the toxicity of reactive oxygen species.It is also used for the synthesis of lipids and cholesterol and during the process of fatty acid chain elongation.

일반 설명

A ubiquitous coenzyme that acts as an electron donor in many reactions utilizing dehydrogenase and reductase enzymes. It is generated by reduction of the electron acceptor NADP+. The following biological pathways involve NADPH: formation of carbohydrate from CO2 during photosynthesis, maintenance of high levels of reduced glutathione in erythrocytes, reduction of thioredoxin.

생물학적 활성

NADPH is an electron donor and a cofactor for many redox enzymes including nitric oxide synthetase.
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Purification Methods

Purification is mostly similar to that of NADH above. [Beilstein 26 III/IV 3671.]

베타-NADPH테트라소듐소금 준비 용품 및 원자재

원자재

준비 용품


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