베타카테닌
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베타카테닌 속성
- 저장 조건
- -70°C
- 물리적 상태
- 완충된 글리세롤 수용액
- 생물학적 소스
- human
- 수용성
- water: soluble
안전
| WGK 독일 | 1 |
|---|
베타카테닌 C화학적 특성, 용도, 생산
용도
Catenin β, GST tagged human has been used:- as a component of protein kinase buffer for in vitro kinase assay
- in in vitro?citrullination assay to characterize β-catenin citrullination
- to perform differentiation factor screening
일반 설명
β-catenins are cytoplasmic proteins that are ubiquitously expressed. These proteins associate with E-cadherin at cellular junctions. CTNNB1 (catenin β-1) belongs to the armadillo family of proteins. This protein possesses a 130 amino acid N-terminal domain, 12 imperfect repeats of 42 amino acids termed arm repeats and a 100 amino acid C-terminal domain. The gene encoding β-catenin is localized on human chromosome 3p22.1.Biochem/physiol Actions
β-catenin interacts with T-cell factor and lymphoid enhancer-binding factor (TCF and LEF) transcription factors and is an essential member of the Wingless-Wnt signal transduction pathway. The adenomatous polyposis coli (APC) tumor-suppressor protein, together with Axin and glycogen synthase kinase 3 β (GSK3β), form a Wnt-regulated signaling complex that mediates phosphorylation-dependent degradation of βcatenin by the proteasome. APC and the Siah-1 E3 ubiquitin-protein ligase-1 mediate a novel β-catenin degradation pathway linking p53 activation to cell cycle control. Activating mutations in the human β-catenin gene have been found in human colon cancer and melanomas. The protein has a role in homeostasis and development.베타카테닌 준비 용품 및 원자재
원자재
준비 용품
베타카테닌 공급 업체
글로벌( 65)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Creative Peptides | |
info@creative-peptides.com | United States | 6083 | 56 |
| Shanghai Han-Xiang Chemical Co., Ltd. | 15971444841 |
amber@biochempartner.com | China | 3061 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 |
422450190@qq.com | China | 10308 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 |
sales@shzbio.com | China | 9964 | 58 |
| Biolab Reagents | 18108604356 |
info@biolabreagent.com | China | 9868 | 58 |
| ACROBiosystems | 18514007688 |
jiaxin.zhao@acrobiosystems.com | China | 1320 | 58 |
| ZSGB-BIO | 02-400-810-9781 400810978 |
sales@zsbio.com | China | 2887 | 58 |
| Kamiya Biomedical Company | 1-+1 206-575-8068 1206-575-8068 |
ordering@k-assay.com | China | 928 | 58 |
| Synaptic Systems GmbH | 49-551-50556-0 |
SynapticSystemsname@qq.com | China | 2373 | 58 |
| Shanghai Bio-Tech Biotechnology Co., Ltd. | 4001683301 |
order@beyotime.com | China | 6067 | 58 |