6-Aminopyridine-3-carboxamide
|
|
6-Aminopyridine-3-carboxamide 속성
- 녹는점
- 245-248 °C (lit.)
- 끓는 점
- 251.97°C (rough estimate)
- 밀도
- 1.2620 (rough estimate)
- 굴절률
- 1.6910 (estimate)
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- insoluble in H2O; insoluble in EtOH; ≥13.7 mg/mL in DMSO
- 물리적 상태
- powder to crystal
- 산도 계수 (pKa)
- 15.66±0.50(Predicted)
- 색상
- 흰색에서 밝은 노란색
- 수용성
- 디메틸설폭사이드(DMSO)에 용해됩니다. 물에 불용성.
- BRN
- 116042
- CAS 데이터베이스
- 329-89-5(CAS DataBase Reference)
안전
- 위험 및 안전 성명
6-Aminopyridine-3-carboxamide C화학적 특성, 용도, 생산
용도
antineoplastic, apoptosis inducer정의
ChEBI: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 6-aminonicotinic acid with ammonia. An inhibitor of the NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase, it interferes with glycolysis resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, such as cisplatin, in killing cancer cells.일반 설명
White crystalline solid.공기와 물의 반응
Insoluble in water.반응 프로필
An amine and amide. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).건강위험
ACUTE/CHRONIC HAZARDS: When heated to decomposition 6-Aminopyridine-3-carboxamide emits toxic fumes of NOx.화재위험
Flash point data for 6-Aminopyridine-3-carboxamide are not available; however, 6-Aminopyridine-3-carboxamide is probably combustible.6-Aminopyridine-3-carboxamide 준비 용품 및 원자재
원자재
준비 용품
6-Aminopyridine-3-carboxamide 공급 업체
글로벌( 179)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 |
sale@chuangyingchem.com | CHINA | 5906 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49374 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29811 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 |
sale04@alfachem.cn | China | 13369 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32165 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23541 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 |
shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52849 | 58 |
6-Aminopyridine-3-carboxamide 관련 검색:
N,N-다이메틸폼아마이드 이소니코틴아마이드 피콜린아미드 아세트아미노펜 4-다이메틸아미노피리딘 포름아미드 2-아미노피리딘 니코틴산아미드 3-아미노피리딘
2-Amino-5-methylpyridine
5-aminopyridine-3-carboxamide
2-AMINOPYRIDINE-4-CARBOXAMIDE
N-Methyl-2-aminopyridine-3-carboxamide
5-AMINOPYRIDINE-2-CARBOXAMIDE,PURITY:95% MIN(HPLC),5-Aminopyridine-2-carboxamide
3-Pyridinecarboxamide,2-amino-(9CI)
3-AMINOPYRIDINE-2-CARBOXAMIDE
6-Aminonicotinic acid
CARBOXAMIDE