109581-93-3(Tacrolimus Monohydrate)
Product Description
109581-93-3
CAS No.
109581-93-3
Chemical Name:
Tacrolimus Monohydrate
CBNumber:
CB4772400
Molecular Formula:
C44H71NO13
Formula Weight:
822.05
MOL File:
Mol file
Tacrolimus Monohydrate Synonyms:
15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, monohydrate, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-
TACROLIMUS HYDRATE/TSUKUBAENOLIDE HYDRATE
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)tetrone
Tacrolimus (150 mg)
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-Methoxycyclohexyl]-1-Methylethenyl]-14,16-diMethoxy-4,10,12,18-tetraMethyl-8-(2-propen-1-yl)-
FK-506 monohydrate, >=98%
Tacrolimus /FK506 monohydrate
,8s*,9e,12r*,14r*,15s*,16r*,18s*,19s*,26ar*))-
Tacrolimus Monohydrate
Property
Melting point:
127-129°
alpha
D23 -84.4° (c = 1.02 in chloroform)
storage temp.
-20°C
solubility
DMSO: soluble20mg/mL
form
powder
color
White to Almost white
Merck
14,9025
InChIKey
NWJQLQGQZSIBAF-MLAUYUEBSA-N
Safety
Hazard Codes :
T
Risk Statements :
25
Safety Statements :
45
RIDADR :
UN 2811 6.1/PG 3
WGK Germany :
3
RTECS :
KD4201200
HazardClass :
6.1
PackingGroup :
III
HS Code :
2934990002
Toxicity:
LD50 i.p. in mice: >200 mg/kg (Kino); LD50 in male, female rats (mg/kg): 57.0, 23.6 i.v.; 134, 194 orally (Ohara)
Tacrolimus Monohydrate
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109581-93-3(Tacrolimus Monohydrate)
Related Search:
15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, monohydrate, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-
TACROLIMUS HYDRATE/TSUKUBAENOLIDE HYDRATE
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)tetrone
Tacrolimus (150 mg)
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-Methoxycyclohexyl]-1-Methylethenyl]-14,16-diMethoxy-4,10,12,18-tetraMethyl-8-(2-propen-1-yl)-
FK-506 monohydrate, >=98%
Tacrolimus /FK506 monohydrate
,8s*,9e,12r*,14r*,15s*,16r*,18s*,19s*,26ar*))-
18-tetramethyl-8-(2-propenyl)-,monohydrate,(3s-(3r*(e(1s*,3s*,4s*)),4s*,5r*
3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-9,10,12,
tacrolimushydrate
tsukubaenolidehydrate
FK-506 MONOHYDRATE
Tacarolimus
15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-te
Tacrolimus Monohydrate CAS 109581-93-3
FK506 Monohydrate[Tacrolimus Hydrate]
135175
CS-1308
FK 506 monohydrate, Tacrolimus
Tacrolimus monohydroate
TacrolimusMonohydrate>
Tacrolimus monohydrate CRS
FR900506 monohydrate
Tacrolimus monohydrate (Fujimycin monohydrate
[3R[E(1S,3S,4S)
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone monohydrate
Tacrolimus monohydrate (Y0001926)
Tacrolimus (1642802)
FK-506
Tacrolimus monohydrate
Lecithin Impurity 9 (L-α-Phosphatidylinositol)
Tacrolimus USP/IP/PH.Eur
Tacrolimus Reference Standard
FK-506|||FR 900506|||Prograf|||FR900506|||Tacrolimus hydrate|||LCP-Tacro|||FK 506
109581-93-3
C44H69NO12H2O
Cell Signaling and Neuroscience
Kinase/Phosphatase Biology
Protein Phosphatase 2B (Calcineurin/PP2B)
Serine/Threonine Phosphatase Inhibitors
BioChemical
Cell Biology
Signalling
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