BACAMPICILLIN HYDROCHLORIDE
BACAMPICILLIN HYDROCHLORIDE
- CAS:
- 37661-08-8
- MF:
- C21H28ClN3O7S
- MW:
- 501.98
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Properties
- Melting point:
- 171-176° (dec)
- alpha
- D20 +161.5°
- storage temp.
- Store at -20°C
- solubility
- Soluble in water, freely soluble in ethanol (96 per cent), soluble in methylene chloride.
- form
- Solid
- color
- Crystals from Me2CO pet ether
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Danger
- Hazard statements
- H317-H334
- Precautionary statements
- P261-P280-P284-P304+P340-P342+P311
- Toxicity
- LD50 in mice (mg/kg): 8529 orally; 176 i.p.; 9475 s.c.; 184 i.v. (Edanaga)
Use
Bacampicillin hydrochloride (Spectrobid) is the hydrochloridesalt of the 1-ethoxycarbonyloxyethyl ester of ampicillin.It is a prodrug of ampicillin with no antibacterial activity.After oral absorption, bacampicillin is hydrolyzed rapidly byesterases in the plasma to form ampicillin.Oral absorption of bacampicillin is more rapid and completethan that of ampicillin and less affected by food.Plasma levels of ampicillin from oral bacampicillin exceedthose of oral ampicillin or amoxicillin for the first 2.5 hoursbut thereafter are the same as for ampicillin and amoxicillin.49 Effective plasma levels are sustained for 12 hours,allowing twice-a-day dosing.
2 India supplier list of "BACAMPICILLIN HYDROCHLORIDE"
- Product Name:BacampicillinHydrochloride(1047300)
- Products Intro:Brand:pharmaffiliates | Product Number:PAUSP1047300
- Company Type: Trader
- Country/Region: INDIA
- Product Name:BACAMPICILLIN HYDROCHLORIDE
- Company Type: Reagent
- Country/Region: INDIA