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ChemicalBook >> CAS DataBase List >>2-Butanone

2-Butanone suppliers

2-Butanone

CAS:
78-93-3
MF:
C4H8O
MW:
72.11

Properties

Melting point:
-87 °C (lit.)
Boiling point:
80 °C (lit.)
Density 
0.805 g/mL at 25 °C (lit.)
vapor density 
2.49 (vs air)
vapor pressure 
71 mm Hg ( 20 °C)
refractive index 
n20/D 1.379(lit.)
FEMA 
2170 | 2-BUTANONE
Flash point:
26 °F
storage temp. 
2-8°C
solubility 
Miscible with acetone, ethanol, benzene, ether (U.S. EPA, 1985), and many other solvents, particularly ketones and aldehydes
form 
Solution
pka
14.7 (quoted, Riddick et al., 1986)
color 
Colorless
Relative polarity
0.327
Odor
Sweet/sharp odor detectable at 2 to 85 ppm (mean = 16 ppm)
PH
pH(1+4, 25℃):6.0~7.0
explosive limit
1.8-11.5%(V)
Odor Threshold
0.44ppm
Odor Type
ethereal
Water Solubility 
290 g/L (20 ºC)
Merck 
14,6072
JECFA Number
278
BRN 
741880
Henry's Law Constant
23.0 at 50.00 °C, 34.1 at 60.00 °C, 50.6 at 70.00 °C, 70.4 at 80.00 °C (headspace-GC, Hovorka et al., 2002)
Exposure limits
TLV-TWA, PEL 590 mg/m3 (200 ppm) (ACGIH, OSHA); STEL 885 mg/m3 (300 ppm) (ACGIH); IDLH 3000 ppm (NIOSH).
Dielectric constant
18.5(20℃)
Stability:
Stable. Highly flammable. Incompatible with oxidizing agents, bases, strong reducing agents. Protect from moisture.
LogP
0.3 at 40℃

Safety Information

Symbol(GHS) 
GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word 
Danger
Hazard statements 
H225-H319-H336
Precautionary statements 
P210-P305+P351+P338
Hazard Codes 
F,Xi,T
Risk Statements 
11-36-66-67-39/23/24/25-23/24/25
Safety Statements 
9-16-45-36/37
OEB
A
OEL
TWA: 200 ppm (590 mg/m3), STEL: 300 ppm (885 mg/m3)
RIDADR 
UN 1193 3/PG 2
WGK Germany 
1
RTECS 
EL6475000
Autoignition Temperature
516 °C
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29141200
Toxicity
LD50 orally in rats: 6.86 ml/kg (Smyth)
IDLA
3,000 ppm

Use

Occupational workers are exposed to 2-butanone by breathing contaminated air in workplaces associated with the production or use of paints, glues, coatings, or cleaning agents. Prolonged exposures to 2-butanone cause symptoms of poisoning such as cough, dizziness, drowsiness, headache, nausea, vomiting, dermatitis, irritation of the nose, throat, skin, and eyes and at very high levels cause drooping eyelids, uncoordinated muscle movements, loss of consciousness, and birth defects. Chronic inhalation studies in animals have reported slight neurological, liver, kidney, and respiratory effects. However, information on the chronic (long-term) effects of 2-butanone (methyl ethyl ketone) in humans is limited.

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