6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE suppliers
6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE
- CAS:
- 545380-34-5
- MF:
- C22H20N4O
- MW:
- 356.42
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Properties
- Melting point:
- 169-175°C
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- DMSO: soluble15mg/mL, clear
- form
- powder
- color
- white to beige
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
- Symbol(GHS)
GHS07,GHS09
- Signal word
- Warning
- Hazard statements
- H302-H410
- Precautionary statements
- P264-P270-P301+P312-P330-P501-P273-P391-P501
- WGK Germany
- 3
Use
QNZ is a novel inhibitor of NFkB which displays potent inhibitory effects on both NFKB transcriptional activation (IC50=11nM) and TNF-α production (IC50=7nM). It dose-dependently inhibited carragenin-induced edema formation in the rat paw model (1mg/Kg). A useful tool to explore the role of NFkB in cellular signaling pathways.
93 supplier list of "6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE"
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