(S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE manufacturers and suppliers

(S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE suppliers

(S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE

CAS:: 745055-91-8

MF:: C15H15N3O6

MW:: 333.3

Suppliers by country/region

Company Type

Properties

Melting point:: 207.9-208.5 °C (decomp)(Solv: water (7732-18-5))

Boiling point:: 603.0±65.0 °C(Predicted)

Density: 1.525±0.06 g/cm3(Predicted)

storage temp.: Store at RT

solubility: DMSO: ≥5mg/mL at 60°C (with warming for 5 minutes)

pka: 2.12±0.10(Predicted)

form: powder

color: white to off-white

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P264-P270-P301+P312-P330-P501

Hazard Codes: Xn

Risk Statements: 22

WGK Germany: 3

Use

Selective and potent GLU K5 (GluR5)-subunit containing kainate receptor antagonist (apparent K D = 402 nM); active enantiomer of UBP 296 ((RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione ). Displays ~ 260-fold selectivity over AMPA receptors. UBP 296 displays ~ 90-fold selectivity over recombinant human GLU K6 - and GLU K2 -containing kainate receptors, has little or no action at NMDA or group I mGlu receptors and selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibres.

You can find (S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.