Almotriptan suppliers
Almotriptan
- CAS:
- 154323-57-6
- MF:
- C17H25N3O2S
- MW:
- 335.46
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Properties
- Boiling point:
- 538.7±60.0 °C(Predicted)
- Density
- 1.27±0.1 g/cm3(Predicted)
- pka
- 16.92±0.30(Predicted)
- form
- Solid
- color
- White to off-white
Safety Information
Use
Almotriptan was first marketed in Spain as a new medicine against acute attacks of migraine. It is the fifth agent belonging to the “triptan” class to be launched after sumatriptan, naratriptan, zolmitriptan and rizatriptan. Almotriptan acts as a dual 5-HT1D/1B agonist with a 35 to 51-fold selectivity versus 5-HT1A and 5-HT7 receptors respectively as well as having insignificant affinity for the most relevant nonserotonergic receptors (K1>1μM). Its agonistic effect on 5-HT,n receptors of trigeminal sensory neurons turns off neurogenic inflammation by inhibiting the release of neuropeptides such as calcitonin gene-related peptide, neurokinin A and substance P.
100 supplier list of "Almotriptan"
$7.00/ 1kg
- Product Name:Almotriptan
- Products Intro:Purity: 99% | Package: 1kg;7USD
- Company Type: Reagent
- Country/Region: CHINA