Calicheamicin suppliers
Calicheamicin
- CAS:
- 108212-75-5
- MF:
- C55H74IN3O21S4
- MW:
- 1368.34
Suppliers by country/region
Company Type
Properties
- alpha
- D26 -124° (c = 0.98%, EtOH)
- Density
- 1.57±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : ≥ 100 mg/mL (73.08 mM);Water : < 0.1 mg/mL (insoluble)
- form
- Solid
- pka
- 7.13±0.60(Predicted)
- color
- White to yellow
Safety Information
Use
Calicheamicin, also known as Calicheamicin gamma(1,I) or Calichemicin gamma1, is an potent enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora. Calicheamicin targets DNA and cause strand scission. Calicheamicin binds with DNA in the minor groove, wherein it then undergos a reaction analogous to the Bergman cyclization to generate a diradical species. This diradical, 1,4-didehydrobenzene, then abstracts hydrogen atoms from the deoxyribose (sugar) backbone of DNA, which ultimately leads to strand scission. The specificity of binding of calicheamicin to the minor groove of DNA is due to the aryltetrasaccharide group of the molecule.
87 supplier list of "Calicheamicin "
$8.00-1.00 / 1kg
- Product Name:Calicheamicin gamma1
- Products Intro:Purity: 99% | Package: 1kg;8USD|25kg;5USD|100kg;1USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,Petrochemicals,Chemical reagents,Intermediates
$7.00/ 1KG
- Product Name: calicheamicin gamma(1)I
- Products Intro:Purity: 99% | Package: 1KG;7USD
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Calicheamicin;Calicheamicin γ1
- Products Intro:Purity: 98.00% | Package: 1 mg;1 mL * 10mM (in DMSO);10 mg;25 mg;5 mg;50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits