Indapamide manufacturers and suppliers

Indapamide suppliers

Properties

Melting point:: 160-162°C

Boiling point:: 110.4°C (rough estimate)

alpha: -0.8～+0.8°(D/20℃) (c=5, C2H5OH)

Density: 1.2895 (rough estimate)

refractive index: 1.6100 (estimate)

storage temp.: -20°C Freezer

solubility: Practically insoluble in water, soluble in ethanol (96 per cent).

pka: pKa (25°) 8.8 ± 0.2

form: Solid

color: White to Off-White

Water Solubility: Soluble in ethanol. Insoluble in water

Merck: 14,4935

BCS Class: 1

InChIKey: NDDAHWYSQHTHNT-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS08

Signal word: Warning

Hazard statements: H361d-H362

Precautionary statements: P202-P260-P263-P264-P270-P308+P313

WGK Germany: 2

RTECS: CV2451200

HS Code: 2935904000

Toxicity: LD50 in rats, mice, guinea pigs (mg/kg): 393-421, 410-564, 347-416 i.p.; 394-440, 577-635, 272-358 i.v.; >3000 all species orally (Kyncl)

Use

Indapamide is currently the most popular non-prescription diuretic antihypertensive drug with good efficacy, stable blood pressure, fewer side effects, etc. it was originally developed for the first time by the french servier (servier) pharmaceutical company. indapamide have diuretic and calcium antagonist dual effect by inhibiting the proximal end of the distal convoluted tubule na+ reabsorption, resulting in diuresis, while by blocking ca2+ influx especially a higher selectivity for vascular smooth muscle to dilate the small blood vessels of the outer periphery, resulting in antihypertensive effect. but the effect to vascular smooth muscle is stronger than the diuretic effect.

You can find Indapamide suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.