PF 477736 suppliers
PF 477736
- CAS:
- 952021-60-2
- MF:
- C22H25N7O2
- MW:
- 419.49
Suppliers by country/region
Company Type
Properties
- Density
- 1.56
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥20mg/mL
- form
- powder
- pka
- 11.79±0.20(Predicted)
- color
- yellow
- InChIKey
- NDEXUOWTGYUVGA-LJQANCHMSA-N
Safety Information
- WGK Germany
- 3
Use
Checkpoint kinase 1 (Chk1) regulates S and G2-M phase cell cycle checkpoints in response to DNA damage. PF-477736 is an ATP-competitive inhibitor of Chk1 with a Ki value of 0.49 nM that demonstrates 100-fold selectivity over Chk2. When used in combination with various chemotherapeutics, PF-477736 abrogates DNA damage-induced cell cycle arrest, potentiating the antiproliferative effects of these compounds in tumor cell lines and xenografts.[Cayman Chemical]
81 supplier list of "PF 477736"
- Product Name:PF 477736
- Products Intro:Purity: 98% | Package: 1KG;10KG;100KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 5-Heptylresorcinol,Methyl 2-heptyl-4,6-dihydroxybenzoate,Cannabinoids Precursors,2,4-dihydroxy-6-propyl-benzoic acid methyl ester,Benzoic acid, 2-hexyl-4,6-dihydroxy-, methyl ester
- Product Name:PF 477736
- Products Intro:Package: 1KG;25kg;200kg;1000kg Elin | CustNote: g-kg-tons,free sample is available.Bottle/drum/IBC.Advantage products,new batches,regular stock, ready for shipment.
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,Petrochemicals,Chemical reagents,Intermediates
You can find PF 477736 suppliers,
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