Bromfenac sodium manufacturers and suppliers

Bromfenac sodium suppliers

Properties

Melting point:: 285 ºC

storage temp.: 2-8°C

solubility: H2O: ≥5mg/mL

form: powder

color: faint yellow to dark yellow

InChIKey: HZFGMQJYAFHESD-UHFFFAOYSA-M

Safety Information

Symbol(GHS): GHS09

Signal word: Warning

Hazard statements: H400

Precautionary statements: P273

Hazard Codes: N

Risk Statements: 50

Safety Statements: 61

RIDADR: UN 3077 9 / PGIII

WGK Germany: 3

Use

Bromfenac Sodium was launched in the US as a potent, orally-active, long lasting peripheral analgesic with antiinflammatory properties. It is structurally similar to ketoprofen and diclofenac and can be prepared in three steps from 2-amino-4’-bromophenone using Gassman’s oxindole synthesis. Duract’s biological effects are a result of its ability to reduce prostaglandin production through inhibition of cyclooxygenase. As a 4-bromo derivative of Amfenac, this modification increased the duration of analgesic activity and antiinflammatory potency. It was also free of any CNS, cardiovascular or autonomic effects. In comparison, 5 mg of Duract was equipotent to 650 mg of ASA and 25 mg was slightly more potent than 400 mg of Ibuprofen.

You can find Bromfenac sodium suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.