Bulaquine manufacturers and suppliers

Bulaquine

CAS:: 79781-00-3

MF:: C21H27N3O3

MW:: 369.46

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Properties

Boiling point:: 616.7±55.0 °C(Predicted)

Density: 1?+-.0.06 g/cm3(Predicted)

pka: 5.60±0.20(Predicted)

Safety Information

Use

Bulaquine is a derivative of primaquine that was introduced in India in combination with chloroquine as a treatment against malaria. The compound is prepared by condensation of primaquine with 3-acetyl-y-butyrolactone in presence of a catalytic amount of base. Bulaquine kills the latent tissue stage (hypnozoites) of the parasite Plasmodium vivax accumulated in the liver and responsible for relapses. Its efficient anti-relapse activity was demonstrated against sporozoite induced Plasmodium cynomolgi infection in rhesus monkey. Bulaquine is safer than primaquine, the preceding candidate against malaria relapse. Although it is stable at pH 7-8, bulaquine is hydrolyzed to primaquine under acidic conditions.

9 supplier list of "Bulaquine"

TargetMol Chemicals Inc.

Gold Member Enterprise Certification

Product Name:Bulaquine
Products Intro:Package: 100 mg；500 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
Company Type: Reagent
Country/Region: UNITED STATES
Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits

TargetMol Chemicals Inc.

Gold Member Enterprise Certification

Product Name:Bulaquine
Products Intro:Package: 50mg;1980USD|100mg;2500USD|25mg;1520USD
Company Type: Trader
Country/Region: UNITED STATES
Main Products: Compound Libraries,Inhibitors & Agonists,Natural Products,Recombinant Proteins,Reagent Kits