CALCEIN-AM suppliers
CALCEIN-AM
- CAS:
- 148504-34-1
- MF:
- C46H46N2O23
- MW:
- 994.86
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Properties
- Melting point:
- >250℃
- Boiling point:
- 982.7±65.0 °C(Predicted)
- Density
- 1.49±0.1 g/cm3(Predicted)
- refractive index
- n
20/D 1.479
- Flash point:
- 85 °C
- storage temp.
- -20°C
- solubility
- DMSO: soluble10mg/mL, clear, colorless to slightly yellow
- pka
- 2.66±0.50(Predicted)
- form
- powder
- color
- Colorless
- λmax
- < 300 nm
- Biological Applications
- Calcium indicators; zinc indicators; cytotoxicity assays; apoptosis assays; viability assays; labile iron pool assays; chemotaxis probes; cell adhesion probes; mitochondrial probes; P-glycoprotein probes;multi-drug resistance probes;treating atherosclerosis,cancer;ischemic disease
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- RIDADR
- NA 1993 / PGIII
- WGK Germany
- 3
- F
- 10-21
Use
Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein (sc-202090), which is an extremely fluorescent and negatively charged molecule. Calcein-AM can be used to stain living cells and in cytoplasmic Schwann cells has been observed to fluoresce bright green. Calcein-AM has been reported to be a neutral substrate for P-glycoprotein (Pgp) and multidrug resistance protein (MRP) and has been used in flow cytometry studies to analyze the function of P-gp and MRP.
108 supplier list of "CALCEIN-AM"
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