CB-839 manufacturers and suppliers

CB-839 suppliers

CB-839

CAS:: 1439399-58-2

MF:: C26H24F3N7O3S

MW:: 571.57

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Properties

Melting point:: 186- 189° C

Density: 1.430±0.06 g/cm3(Predicted)

storage temp.: +2C to +8C

solubility: Soluble in DMSO.

form: Yellow solid

pka: 8.25±0.50(Predicted)

color: Pale yellow

Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H315-H319-H335

Precautionary statements: P261-P305+P351+P338

Use

In the mouse TNBC model, single agent CB-839 (200 mg/kg, p.o.) suppresses tumor growth by 61% relative to vehicle control. In the mouse JIMT-1 xenograft model, CB-839 alone (200 mg/kg, p.o.) results in 54% tumor growth inhibition (TGI) relative to vehicle control, combination of CB-839 (200 mg/kg, p.o.) with paclitaxel (10 mg/kg, p.o.) largely suppresses the regrowth of the tumors resulting in a TGI relative to vehicle control of 100%.

You can find CB-839 suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.