CEPHALOTAXINE manufacturers and suppliers

CEPHALOTAXINE suppliers

CEPHALOTAXINE

CAS:: 24316-81-2

MF:: C21H42O3

MW:: 342.56

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Properties

Melting point:: 131-134°C

storage temp.: Refrigerator

solubility: Chloroform, Methanol

form: Solid

color: White

Safety Information

Use

Cephalotaxine is a naturally occurring benzazepine alkaloid isolated from Cephalotaxus harringtonia. Composition comprising cephalotaxine alkaloids is used as an antiangiogenic agent for the treatment of a host with an angiogenic disease or for prophylactic treatment of a host to inhibit the onset or progression of an angiogenic disease. Combined with an antiproliferative agent, cephalotaxine is also used for treatment of a host with cellular proliferative disease. Though cephalotaxine is inactive, its ester derivatives have shown antiviral, antitumor, and anticancer properties. Cephalatoxin esters (harringtonine, sioharringtonine, homoharringtonine) have shown significant activity against experimental P388 leukemia and against L-1210 leukemia in mice.

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