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ChemicalBook >> CAS DataBase List >>Ephedrine

Ephedrine suppliers

Ephedrine

CAS:
299-42-3
MF:
C10H15NO
MW:
165.24

Properties

Melting point:
37-39 °C(lit.)
Boiling point:
255 °C(lit.)
alpha 
-41 º (c=5, 1M HCl)
Density 
1.124 g/mL at 25 °C(lit.)
refractive index 
1.4820 (estimate)
Flash point:
186 °F
storage temp. 
Refrigerator (+4°C)
pka
pKa 8.02 (Uncertain);9.5 (Uncertain)
optical activity
[α]21/D 41°, c = 5 in 1 M HCl
Water Solubility 
47.62g/L(25 ºC)
Merck 
13,3639
BRN 
2208730
Stability:
Stable. Combustible. Incompatible with strong acids, acid chlorides, acid anhydrides, strong oxidizing agents. May discolour in light.

Safety Information

Symbol(GHS) 
GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word 
Danger
Hazard statements 
H302-H314-H317
Precautionary statements 
P260-P270-P280-P301+P312-P303+P361+P353-P305+P351+P338
Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
22-25
WGK Germany 
1
RTECS 
KB0700000
3-10
Hazard Note 
Harmful
HS Code 
29394100
Toxicity
LD50 oral in rat: 600mg/kg

Use

ephedrine: An alkaloid,C6H5CH(OH)CH(CH3)NHCH3 found inplants of the genus Ephedra, onceused as a bronchodilator in the treatmentof asthma. It is also used as astimulant and appetite suppressant.Structurally, it is a phenylethylamineand is similar to amphetamines, althoughless active. It is, however,widely used in the illegal synthesis ofmethamphetamine. The moleculehas two chiral centres. If the stereo- chemical conformations are opposite(i.e. 1R,2S or 1S,1R) the nameephedrine is used. If the conformationsare the same (1R,2R or 1S,2S)then the compound is called pseudoephedrine.

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