GSK 343 suppliers
GSK 343
- CAS:
- 1346704-33-3
- MF:
- C31H39N7O2
- MW:
- 541.69
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Properties
- Boiling point:
- 797.4±60.0 °C(Predicted)
- Density
- 1.26±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble15mg/mL, clear
- form
- powder
- pka
- 11.84±0.10(Predicted)
- color
- , white to beige to brown
- InChIKey
- ULNXAWLQFZMIHX-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P301+P312+P330
- Hazard Codes
- Xn
- Risk Statements
- 22
- WGK Germany
- 3
Use
GSK343 inhibits trimethylation of H3K27 (H3K27me3) with IC50 of 174 nM in HCC1806 breast cancer cells. GSK343 potently inhibits cell proliferation in breast cancer cells and prostate cancer cells, and the prostate cancer cell line LNCaP is the most sensitive to GSK343, with IC50 of 2.9 μM. GSK343 significantly suppresses the growth of EOC cells cultured in 3D matrigel extracellular matrix (ECM), which mimics the tumor microenvironment in vivo. In addition, GSK343 also induces apoptosis of EOC cells in 3D and significantly inhibits the invasion of EOC cells.
96 supplier list of "GSK 343"
- Product Name:GSK 343
- Products Intro:Purity: 95%+ | Package: 1g;5g;10g;25g;50g;100g; | CustNote: accept Custom Synthesis Services, support large packing
- Company Type: Trader
- Country/Region: CHINA
You can find GSK 343 suppliers,
manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here.
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