Hexachlorophene manufacturers and suppliers

Hexachlorophene suppliers

Properties

Melting point:: 163-165 °C(lit.)

Boiling point:: 519.9°C (rough estimate)

Density: 1.6065 (rough estimate)

refractive index: 1.5550 (estimate)

Flash point:: 11 °C

storage temp.: 2-8°C

solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml

form: crystalline

pka: pKa 4.89 ± 0.02(H2O,t = 25.0±0.1,I=0.1(NaCl)) (Uncertain)

color: off-white to tan

Water Solubility: 19mg/L(25 ºC)

λmax: 300nm(MeOH)(lit.)

Merck: 14,4680

BRN: 2064407

Stability:: Stable. Incompatible with alkalies, akaline earths, tweens, strong oxidizers.

CAS DataBase Reference: 70-30-4(CAS DataBase Reference)

IARC: 3 (Vol. 20, Sup 7) 1987

NIST Chemistry Reference: 2,2'-Methylenebis(3,4,6-trichlorophenol)(70-30-4)

EPA Substance Registry System: Hexachlorophene (70-30-4)

Safety Information

Symbol(GHS): GHS06,GHS09

Signal word: Danger

Hazard statements: H301+H311-H410

Precautionary statements: P264-P270-P273-P280-P301+P310-P302+P352+P312

Hazard Codes: T,N,F

Risk Statements: 24/25-50/53-52/53-39/23/24/25-23/24/25-11-51/53

Safety Statements: 20-37-45-60-61-36/37-16

RIDADR: UN 2875 6.1/PG 3

WGK Germany: 3

RTECS: SM0700000

HazardClass: 6.1(b)

PackingGroup: III

HS Code: 29072990

Hazardous Substances Data: 70-30-4(Hazardous Substances Data)

Toxicity: LD50 in adult male, female rats (mg/kg): 66, 57 orally (Gaines, Linder)

Use

Hexachlorophene, an antimicrobial agent, was introduced in 1948 in proprietary liquid preparations and powders and was subsequently used extensively as a topical antiseptic. By the early 1970s its use in infants had been conclusively demonstrated to cause encephalopathy as a result of transdermal absorption. More recently it has been suggested that the drug has a teratogenic potential. Many regulatory authorities have placed rigorous restrictions on the medicinal use of hexachlorophene, particularly in preparations intended for infants. However, its use still commonly remains permissible at low concentrations as a preservative in toiletries and cosmetics. (Reference: (WHODI) WHO Drug Information, 3, 6, 1978)

You can find Hexachlorophene suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.