Medroxyprogesterone Acetate manufacturers and suppliers

Medroxyprogesterone Acetate suppliers

Properties

Melting point:: 206-207 °C(lit.)

alpha: D +61° (in chloroform)

Boiling point:: 432.7°C (rough estimate)

Density: 1.0346 (rough estimate)

refractive index: 48 ° (C=1, Dioxane)

storage temp.: Sealed in dry,2-8°C

solubility: Practically insoluble in water, freely soluble in methylene chloride, soluble in acetone, sparingly soluble in ethanol (96 per cent)

form: Solid

color: White

Water Solubility: <0.1 g/100 mL at 23 ºC

Merck: 13,5817

BRN: 2066112

BCS Class: 2,3,1

Stability:: Stable, but weakly air and light sensitive. Incompatible with strong oxidizing agents.

CAS DataBase Reference: 71-58-9(CAS DataBase Reference)

IARC: 2B (Vol. 21, Sup 7) 1987

EPA Substance Registry System: Medroxyprogesterone acetate (71-58-9)

Safety Information

Symbol(GHS): GHS08

Signal word: Warning

Hazard statements: H351-H413

Precautionary statements: P201-P202-P273-P280-P308+P313-P405

Hazard Codes: Xn

Risk Statements: 40-48

Safety Statements: 22-36/37/39-45

WGK Germany: 3

RTECS: TU5010000

HS Code: 29372390

Use

A depot preparation containing 150 mg medroxyprogesterone acetate was introduced over 20 years ago for use as a long-acting injectable contraceptive. Subsequently, positive results of carcinogenicity studies carried out in beagle bitches led to refusal of registration in the United States. These findings were later considered irrelevant to contraceptive use in women and the drug was approved by the Food and Drug Administration. Menstrual irregularities are the most common adverse effect associated with depot medroxyprogesterone acetate. Risk-benefit judgements differ significantly from country to country, having regard to differing national circumstances. The preparation is, however, widely available and is included in the WHO Model List of Essential Drugs. (Reference: (WHTAC4) The Use of Essential Drugs, 4th Report of the WHO Expert Committee, 796, , 1990)

You can find Medroxyprogesterone Acetate suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.