Mexiletine hydrochloride manufacturers and suppliers

Mexiletine hydrochloride suppliers

Properties

Melting point:: 200-203°C

Density: 1.12 g/cm3

storage temp.: 2-8°C

solubility: ethanol: 50 mg/mL

form: powder

pka: 9.0(at 25℃)

color: white

λmax: 272nm(MeOH)(lit.)

Merck: 14,6169

Stability:: Hygroscopic

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P301+P312+P330

Hazard Codes: Xn

Risk Statements: 20/21/22-36/37/38-22

Safety Statements: 36-26

WGK Germany: 3

RTECS: KR9300000

HS Code: 2922190900

Toxicity: LD50 in male, female rats, mice, rabbits (mg/kg): 350, 400, 310, 400, 180, 160 orally; in male, female rats, mice (mg/kg): 27, 30, 43, 50 i.v. (Kast)

Use

Mexiletine hydrochloride, like class I antiarrhythmicagents, blocks the fast Na channel in cardiac cells. It isespecially effective on the Purkinje fibers in the heart. Thedrug increases the threshold of excitability of myocardialcells by reducing the rate of rise and amplitude of the actionpotential and decreases automaticity.Mexiletine hydrochloride is used for long-term oral prophylaxisof ventricular tachycardia. The drug is given in200- to 400-mg doses every 8 hours.

You can find Mexiletine hydrochloride suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.