Pasireotide suppliers
PASIREOTIDE
- CAS:
- 396091-73-9
- MF:
- C58H66N10O9
- MW:
- 1047.23
Suppliers by country/region
Company Type
Properties
- Boiling point:
- 1351.4±65.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Powder
- pka
- 11.86±0.46(Predicted)
- Sequence
- cyclo[Tyr(Bzl)-Phe-Hyp(Bom)-Phg-D-Trp-Lys]
- InChIKey
- VMZMNAABQBOLAK-PHODJXESNA-N
- CAS DataBase Reference
- 396091-73-9
Safety Information
Use
In April 2012, the European Commission approved pasireotide for the treatment of Cushing’s Disease (CD) in adult patients who have not responded to surgical interventionor forwhomsurgery is not anoption.Pasireotide was approved for the same indication by the US FDA in December of 2012. Pasireotide (also known as SOM230) is a cyclohexapeptide that acts as a somatostatin analogue to inhibit the release of ACTH. Somatostatins are cyclic peptides of 14 and 28 amino acids that play animportant role inregulating endocrineandexocrine release inmany tissues through an inhibitory mechanism. There are five known subtypes of somatostatin receptors (SSTRs). Natural somatostatins bind with high affinity to all five subtypes, however, their therapeutic use is limited by rapid degradation in plasma. Pasireotide arose fromefforts to identify a somatostatinmimetic with long-lasting inhibitory effects. Starting with a 14-amino acid somatostatin peptide, a systematic alanine scan revealed residues that were essential for receptor sub-type binding, including key b-turn regions and adjacent residues. Placing the key structural elements as unnatural amino acids in a cyclohexapeptide backbone gave pasireotide.
84 supplier list of "PASIREOTIDE"
$0.00-0.00 / 1BOX
- Product Name:Pasireotide
- Products Intro:Purity: 99%|Package: 1BOX;0.00;USD|10BOX;0.00;USD|100BOX;0.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Semaglutide,Tirzepatide,Retatrutide,Liaglutide
$70.00-700.00 / 1kg
- Product Name:PASIREOTIDE
- Products Intro:Purity: 0.99|Package: 1kg;70.00;USD|10kg;700.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Fine Chemical,API,Raw Material,Pharmaceutical Compounds,Others
- Product Name:pasireotide
- Products Intro:Purity: 98% | Package: 1KG;10KG;50KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Pasireotide
- Products Intro:Purity: >98% | Package: 5mg | CustNote: BOC Sciences also provides custom synthesis services for Pasireotide.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Pasireotide
- Products Intro:Purity: .99 | Package: 5KG;1KG；5KG;25KG | CustNote: Payment:Paypal/bitcoin/western union/bank transfer
- Company Type: Trader
- Country/Region: CHINA
- Main Products: hgh191aa,peptides,sarms
$7.00/ 1KG
- Product Name:PASIREOTIDE
- Products Intro:Purity: 99% | Package: 1KG;7USD
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Pasireotide
- Products Intro:Purity: 0.99 | Package: 1KG;5KG;100KG;1000KG | CustNote: 1KG,5KG,25KG,200KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Pasireotide
- Products Intro:Purity: 0.99 | Package: 5KG;43KG | CustNote: Factory direct sales
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: lead acetate,Lead oxide,PMK ethyl glycidate,BMK Glycidic Acid,Diethyl(phenylacetyl)malonate
- Product Name:Pasireotide；SOM 320;SOM 230
- Products Intro:Purity: 98.00% | Package: 100 mg；500 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:Pasireotide
- Products Intro:Purity: 0.99 | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA