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ChemicalBook >> CAS DataBase List >>Phenobarbital

Phenobarbital suppliers

Phenobarbital

CAS:
50-06-6
MF:
C12H12N2O3
MW:
232.24

Properties

Melting point:
174°C
Boiling point:
374.4°C (rough estimate)
Density 
1.2243 (rough estimate)
refractive index 
1.6660 (estimate)
Flash point:
11 °C
storage temp. 
2-8°C
solubility 
Very slightly soluble in water, freely soluble in ethanol (96 per cent). It forms water-soluble compounds with alkali hydroxides, carbonates and ammonia.
pka
7.3, 11.8(at 25℃)
form 
Solid
color 
White to Off-White
Water Solubility 
<0.01 g/100 mL at 14 ºC
Merck 
13,7319
BCS Class
1
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.

Safety Information

Symbol(GHS) 
GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS06
Signal word 
Danger
Hazard statements 
H317-H351-H301+H311+H331
Precautionary statements 
P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P201-P202-P281-P308+P313-P405-P501
Hazard Codes 
T,F
Risk Statements 
61-25-40-43-39/23/24/25-23/24/25-11
Safety Statements 
53-36/37-45-16
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
CQ6825000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2933530000
Toxicity
LD50 orally in rats: 162 ±14 mg/kg (Goldenthal)

Use

Phenobarbital, also known as Rumina and Canaa, is white andglossy crystalline powder. This product has sedative, hypnotic and anticonvulsant effects, and can resist epilepsy. It is effective for large epileptic seizures, localized seizures and status epilepticus. It also enhances the role of antipyretic analgesics, and can induce liver microsomal glucuronosyltransferase activity, promote bilirubin and glucuronic acid binding, reduce plasma bilirubin concentration, and treat neonatal cerebral nucleus jaundice.

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