Rebeprazole sodium suppliers
Rebeprazole sodium
- CAS:
- 117976-90-6
- MF:
- C18H21N3O3S.Na
- MW:
- 382.43
Suppliers by country/region
Company Type
Properties
- Melting point:
- 140-141°C dec.
- storage temp.
- -20°C
- solubility
- H2O: soluble10mg/mL (clear solution)
- form
- powder
- color
- white to beige
- Merck
- 14,8089
- Stability:
- Hygroscopic
- InChIKey
- KRCQSTCYZUOBHN-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H413
- Precautionary statements
- P264-P270-P273-P301+P312-P501
- WGK Germany
- 3
- HS Code
- 2933399090
Use
Rebeprazole sodium was launched as Pariet in Japan, its first market, for the treatment of peptic ulcers including gastric and duodenal ulcers. From 4-chloro- 2,3-dimethylpyridine N-oxide, a six step synthesis allows access to the basic skeleton after successive condensations. Rabeprazole, a structural analog of Omeprazole, the first compound to have been marketed in this class up to now, is reported to be a more potent inhibitor of gastric H+/K+-adenosine triphosphate (ATPase) ; a common mechanism of action of this chemical class involves the conversion at low pH to a reactive sulphonamide that itself binds to cysteine residues located on the enzyme. Moreover, rabeprazole showed an antibacterial activity against Helicobacter Pylori, with a MIC90 of 1.56 μg/ml. Rebeprazole sodium has a faster onset of action compared with omeprazole, but a shorter duration of action, being extensively and rapidly metabolized in several animal species. In clinical studies in patients with gastric ulcers, 10 and 20 mg rabeprazole sodium once-daily significantly inhibited basal and stimulated acid output. Rabeprazole is awaiting registration in the US for treatment of gastrooesophageal reflux disease (GORD) and other pathologic hypersecretory conditions including Zollinger-Ellison syndrome. Rebeprazole sodium is White Crystalline Solid Rebeprazole sodium is a partially reversible gastric proton pump inhibitor
536 supplier list of "Rebeprazole sodium"
- Product Name:Rabeprazole Sodium Enteric-Coated Capsules
- Products Intro:Purity: GMP / DMF|Package: 25Kg/Bag;0.00USD
- Company Type: Trader
- Country/Region: CHINA
$0.00/ 25KG
- Product Name:Rebeprazole sodium
- Products Intro:Purity: 99% | Package: 25KG
- Company Type: Service provider
- Country/Region: CHINA
$9.00-9.00 / 1KG
- Product Name:Rebeprazole Sodium
- Products Intro:Purity: 98%|Package: 1KG;9.00;USD|1KG;9.00;USD
- Company Type: Trader
- Country/Region: CHINA
$0.00-0.00 / 1Kg
- Product Name:Rabeprazole sodium
- Products Intro:Purity: 99%; USP/EP/CP | Package: 1Kg;|5Kg;|25Kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Rebeprazole sodium
- Products Intro:Purity: 99.8% | Package: 1kg;35USD|25kg;30USD|100kg;25USD
- Company Type: Trader
- Country/Region: CHINA
$1.00/ 1kg
- Product Name:Rebeprazole sodium
- Products Intro:Purity: 99% | Package: 1kg;1USD
- Company Type: Reagent
- Country/Region: CHINA
$10.00/ 1KG
- Product Name:Rebeprazole sodium
- Products Intro:Purity: 99% | Package: 1KG;10USD
- Company Type: Trader
- Country/Region: CHINA