Tafenoquine manufacturers and suppliers

Tafenoquine suppliers

Tafenoquine

CAS:: 106635-80-7

MF:: C24H28F3N3O3

MW:: 463.49

Suppliers by country/region

Company Type

Properties

Melting point:: 60 - 63°C

Boiling point:: 565.6±50.0 °C(Predicted)

Density: 1.237±0.06 g/cm3(Predicted)

storage temp.: 4°C

solubility: DMSO (Slightly), Methanol (Slightly)

pka: 10.36±0.10(Predicted)

form: Solid

color: Dark Orange to Very Dark Orange

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H315-H319-H335

Precautionary statements: P261-P305+P351+P338

Use

Etaquine. A synthetic 8-aminoquinoline, formulated as the succinate for oral administration. Tafenoquine is an effective schizonticide against P. falciparum and P. vivax. It is also active against the pre-erythrocytic stages of these species and the hypnozoites of P. vivax. A dosage of 100 mg base corresponds to 125 mg salt. Oral absorption is slow with a maximum plasma concentration reached after 12 h. The half-life is 2 weeks, significantly longer than that of primaquine. It is not eliminated via the kidneys. Toxicity and side effects are similar to those of primaquine. Development of methemoglobinemia is common. Patients with G6PD deficiency may develop severe hemolysis. It is in clinical development for the treatment and prophylaxis of P. vivax malaria and for the treatment of P. falciparum infection.

You can find Tafenoquine suppliers, manufacturers, and distributors from countries such as China, United States and the Germany here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.