Trandolapril manufacturers and suppliers

Trandolapril suppliers

Properties

Melting point:: 122-123°C

Boiling point:: 626.0±55.0 °C(Predicted)

Density: 1.181±0.06 g/cm3(Predicted)

storage temp.: 2-8°C

solubility: DMSO: ≥20mg/mL

form: white powder

pka: 3.15±0.20(Predicted)

color: White to Off-White

InChIKey: VXFJYXUZANRPDJ-WTNASJBWSA-N

SMILES: N1(C(=O)[C@@H](N[C@H](C(OCC)=O)CCC2=CC=CC=C2)C)[C@]2([H])[C@]([H])(CCCC2)C[C@H]1C(O)=O

Safety Information

Symbol(GHS): GHS08

Signal word: Danger

Hazard statements: H360D

Precautionary statements: P201-P202-P280-P308+P313-P405-P501

WGK Germany: 3

RTECS: NL6015178

HS Code: 2933995300

Use

Trandolapril is a new ACE inhibitor that is rapidly hydrolyzed, mainly in the liver, to its biologically active form, trandolaprilat. Compared with all other ACE inhibitors, trandolaprilat is reported to have the highest lipophilicity and the most prolonged ACE inhibitory activity. In hypertensive patients, trandolapril at a dose of 2 mg reduces blood pressure consistently throughout the 24 hour period after intake, making it one of the best once a day antihypertensive drugs. It has also been demonstrated to inhibit aortic atherosclerosis in the hyperlipidemic rabbit.

You can find Trandolapril suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.