UCN-01 suppliers
UCN-01
- CAS:
- 112953-11-4
- MF:
- C28H26N4O4
- MW:
- 482.53044
Suppliers by country/region
Company Type
Properties
- Boiling point:
- 705.7±60.0 °C(Predicted)
- Density
- 1.63±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: >5mg/mL
- form
- Tan solid
- pka
- 12.25±0.70(Predicted)
- color
- light yellow
- optical activity
- [α]20/D 130 to 160°, c = 0.2 in DMSO
Safety Information
- WGK Germany
- 3
- RTECS
- KC6600010
- Toxicity
- mouse,LD50,intraperitoneal,25mg/kg (25mg/kg),Journal of Antibiotics. Vol. 42, Pg. 571, 1989.
Use
UCN-01 is an indolocarbazole isolated from a high staurosporine-producing Streptomyces culture. UCN-01 inhibits protein kinase C (PKC) and cyclin-dependant kinase 2 (CDK2), resulting in accumulation of cells in the G1 phase and induction of apoptosis. UCN-01 also enhances the cytotoxicity of other anti-cancer drugs, such as DNA-damaging agents and anti-metabolite drugs, through putative abrogation of G2 and/or S phase accumulation induced by the latter agents.
50 supplier list of "UCN-01"
![(5S,6R,7R,9R,16R)-16-Hydroxy-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14(5H)-one](/images/pro-3.jpg)
- Product Name:(5S,6R,7R,9R,16R)-16-Hydroxy-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14(5H)-one
- Products Intro:Purity: 95%+ | Package: 1g;5g;10g;25g;50g;100g; | CustNote: accept Custom Synthesis Services, support large packing
- Company Type: Trader
- Country/Region: CHINA
- Main Products: cof,mof
![UCN-01](/images/pro-3.jpg)
-
1mg$550.005mg$2300.0010mg$4000.00
- Product Name:UCN-01
- Products Intro:Brand:csnpharm | Product Number:CSN23871
- Company Type: Trader
- Country/Region: UNITED STATES
You can find UCN-01 suppliers,
manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here.
Browse to the tetrahydrofuran product information displayed by the supplier,
as well as the supplier's contact and capability information.