Vitamin E manufacturers and suppliers

Vitamin E suppliers

Properties

Melting point:: 2.5-3.5 °C

Boiling point:: 200-220 °C0.1 mm Hg(lit.)

alpha: 24 º (c=2, in isooctane 25 ºC)

Density: 0.95 g/mL at 25 °C(lit.)

refractive index: n20/D 1.505(lit.)

Flash point:: 253 °C

storage temp.: -20°C

solubility: Practically insoluble in water, freely soluble in acetone, in anhydrous ethanol, in methylene chloride and in fatty oils.

pka: 11.40±0.40(Predicted)

form: oil

color: clear yellow

Odor: lt. yel. to red visc. oil, nearly odorless

Water Solubility: INSOLUBLE

Merck: 14,9495

BRN: 4712525

Stability:: Stable. Combustible. May be sensitive to light and air. Incompatible with strong oxidizing agents.

LogP: 10.962 (est)

CAS DataBase Reference: 59-02-9(CAS DataBase Reference)

NIST Chemistry Reference: Vitamin e(59-02-9)

EPA Substance Registry System: 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)- (59-02-9)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H315-H319-H335

Precautionary statements: P261-P305+P351+P338

Hazard Codes: Xi

Risk Statements: 36/37/38

Safety Statements: 23-24/25-37/39-26

WGK Germany: 1

RTECS: DJ2900000

F: 8-10-23

HS Code: 29362800

Hazardous Substances Data: 59-02-9(Hazardous Substances Data)

Use

Vitamin E is a viscous yellow oil which is distilled at high vacuum. It has max at 294nm (E1cm 1% 71). It is oxygen and light sensitive and is best stored as its stable D--acetate [58-95-7] which is purified by evaporative distillation at b 180-200o(bath temperature)/0.7mm, and has [] D 25 +3.3o (c 5.1, EtOH). It forms needles at -30o and has m 26.5-27.5o, [] D 25 +0.25o (c 10, CHCl3). [NMR: Cohen et al. Helv Chim Acta 6 4 1158 1981, Burton & Ingold Acc Chem Res 1 9 194 1986, Karrer et al. Helv Chim Acta 2 1 520 1938, Robeson J Am Chem Soc, 64 1487 1942, 65 1660 1943.] Of the eight isomers the D--isomer is the most active. [See W. Friedrich “Vitamins” Walter de Guyter Publ, Berlin 1988.] [Beilstein 17/4 V 168.]

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