WYE-354 suppliers
WYE-354
- CAS:
- 1062169-56-5
- MF:
- C24H29N7O5
- MW:
- 495.53
Suppliers by country/region
Company Type
Properties
- Density
- 1.46
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- ≥49.6 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
- form
- solid
- pka
- 13.42±0.70(Predicted)
- color
- White to off-white
Safety Information
Use
A pyrazolopyrimidines derivative that is a potent and ATP-competitive mTOR inhibitor with much reduced activity against PI 3-Kα or PI 3-Kγ. WYE-354 is equally potent against mTORC1 and mTORC2 activities in HEK293 immune complex kinase assays using S6K and Akt as the respective substrate (IC50 <200 nM; [ATP] = 100 μM) and effectively blocks cellular phosphorylation of S6K on T389 and Akt on S473 both in cultures and in a murine xenograft model, resulting in a significant suppression of PC3MM2-derived tumor growth (by 86% on day 7; 50 mg/kg, i.p twice per day) in vivo.
79 supplier list of "WYE-354"
- Product Name:WYE-354
- Products Intro:Purity: 0.99 | Package: 5MG;10MG;50MG;100MG,1G,5G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:WYE-354
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name:wye 354
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:WYE-354
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:mTOR Kinase Inhibitor II WYE-354 WYE354
- Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: Wye354 Wye-354
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms
- Product Name:WYE-354；WYE 354;WYE354
- Products Intro:Package: 1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；200 mg；25 mg；5 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:WYE-354
- Products Intro:Purity: 0 | Package: 1g; 5g; 25g; 1kg; 5kg; 25kg | CustNote: 0
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediate
- Product Name:WYE-354
- Products Intro:Purity: >=98% | Package: $53.9/5mg;$205.9/25mg;$741.9/100mg;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:WYE-354
- Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A925115
- Company Type: Reagent
- Country/Region: CHINA
You can find WYE-354 suppliers,
manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here.
Browse to the tetrahydrofuran product information displayed by the supplier,
as well as the supplier's contact and capability information.