YK-4-279 suppliers
YK-4-279
- CAS:
- 1037184-44-3
- MF:
- C17H13Cl2NO4
- MW:
- 366.2
Suppliers by country/region
Company Type
Properties
- Melting point:
- 149-151℃
- Boiling point:
- 608.9±55.0 °C(Predicted)
- Density
- 1.456
- storage temp.
- Store at -20° C.
- solubility
- insoluble in H2O; ≥16.35 mg/mL in DMSO; ≥24.25 mg/mL in EtOH with ultrasonic
- form
- Powder
- pka
- 10.43±0.20(Predicted)
- color
- White to off-white
Safety Information
Use
An oncogenic fusion protein found in Ewing's sarcoma, a family of undifferentiated tumors which occur throughout the body. The binding of ES-FLI1 to RNA helicase A (RHA) promotes its oncogenic function. Inhibits protein-protein interactions between ES-FLI1 and RHA. At 10 μM, YK-4-279 blocks RHA binding to ES-FLI1 and induces apoptosis of a panel of Ewing's sarcoma tumor cell lines with IC50 values ranging from 0.5 to 2 μM.1 At 1.5 mg per dose, YK-4-279 reduces the growth of Ewing's sarcoma orthotopic xenografts in mice after treatment with the inhibitor for two weeks.
84 supplier list of "YK-4-279"
$1.00/ 1KG
- Product Name:4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one
- Products Intro:Purity: Min98% HPLC | Package: 1KG;1USD
- Company Type: Trader
- Country/Region: CHINA
- Product Name:4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxo-ethyl]indolin-2-one
- Products Intro:Purity: 0.98 | Package: 100KG;25KG;10KG;1KG
- Company Type: Trader
- Country/Region: CHINA
You can find YK-4-279 suppliers,
manufacturers, and distributors from countries such as CHINA, United States and the The Netherlands here.
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