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ChemicalBook >> CAS DataBase List >> 1-EBIO

1-EBIO

1-EBIO price.
  • $27 - $1091
  • Product name: 1-EBIO
  • CAS: 10045-45-1
  • MF: C9H10N2O
  • MW: 162.19
  • EINECS:233-148-1
  • MDL Number:MFCD00005715
  • Synonyms:1-Ethyl-1H-benzimidazole-2(3H)-one;1-Ethyl-2,3-dihydro-1H-benzimidazole-2-one;EBIO;1-Ethyl-2-benzimidazolinone,98%;Einecs 233-148-1;1-EB10;1-ethyl-1,3-dihydro-2H-benzimidazol-2-one(SALTDATA: FREE);1-EBIO, 1-Ethyl-2-benzimidazolinone
44 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • Alichem
  • Ambeed
  • ApexBio Technology
  • Apolloscientific
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemBridge Corporation
  • Chemenu
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 50mg
  • 500mg
  • 2g
  • 10
  • 50
  • 10mM(in 1mL DMSO)
  • 100mg
  • 250mg
  • 1g
  • 5g
  • 10g
  • 25g
  • 500g
  • ManufacturerAHH
  • Product numberMT-12043
  • Product description1-Ethyl-2-benzimidazolinone 99%
  • Packaging500g
  • Price$478
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberZ6277
  • Product description1-Ethylbenzimidazolinone
  • Packaging25g
  • Price$1091
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number10045451
  • Product description1-Ethyl-1H-benzo[d]imidazol-2(3H)-one
  • Packaging5g
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number10045451
  • Product description1-Ethyl-1H-benzo[d]imidazol-2(3H)-one
  • Packaging10g
  • Price$375.72
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number10045451
  • Product description1-Ethyl-1H-benzo[d]imidazol-2(3H)-one
  • Packaging25g
  • Price$795.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147983
  • Product description1-Ethyl-1H-benzo[d]imidazol-2(3H)-one 97%
  • Packaging100mg
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147983
  • Product description1-Ethyl-1H-benzo[d]imidazol-2(3H)-one 97%
  • Packaging250mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147983
  • Product description1-Ethyl-1H-benzo[d]imidazol-2(3H)-one 97%
  • Packaging1g
  • Price$91
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147983
  • Product description1-Ethyl-1H-benzo[d]imidazol-2(3H)-one 97%
  • Packaging5g
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147983
  • Product description1-Ethyl-1H-benzo[d]imidazol-2(3H)-one 97%
  • Packaging25g
  • Price$1025
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6563
  • Product description1-EBIO
  • Packaging10mM(in 1mL DMSO)
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6563
  • Product description1-EBIO
  • Packaging10mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR954133
  • Product description1-Ethylbenzimidazolinone 98%
  • Packaging1g
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR954133
  • Product description1-Ethylbenzimidazolinone 98%
  • Packaging5g
  • Price$345
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546156
  • Product description1-EbIO >98%
  • Packaging10mg
  • Price$136
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546156
  • Product description1-EbIO >98%
  • Packaging50mg
  • Price$304.3
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-12043 1-Ethyl-2-benzimidazolinone 99% 500g $478 2021-12-16 Buy
AK Scientific Z6277 1-Ethylbenzimidazolinone 25g $1091 2021-12-16 Buy
Alichem 10045451 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one 5g $233 2021-12-16 Buy
Alichem 10045451 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one 10g $375.72 2021-12-16 Buy
Alichem 10045451 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one 25g $795.6 2021-12-16 Buy
Ambeed A147983 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one 97% 100mg $27 2021-12-16 Buy
Ambeed A147983 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one 97% 250mg $38 2021-12-16 Buy
Ambeed A147983 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one 97% 1g $91 2021-12-16 Buy
Ambeed A147983 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one 97% 5g $300 2021-12-16 Buy
Ambeed A147983 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one 97% 25g $1025 2021-12-16 Buy
ApexBio Technology B6563 1-EBIO 10mM(in 1mL DMSO) $42 2021-12-16 Buy
ApexBio Technology B6563 1-EBIO 10mg $97 2021-12-16 Buy
Apolloscientific OR954133 1-Ethylbenzimidazolinone 98% 1g $115 2021-12-16 Buy
Apolloscientific OR954133 1-Ethylbenzimidazolinone 98% 5g $345 2021-12-16 Buy
Biorbyt Ltd orb546156 1-EbIO >98% 10mg $136 2021-12-16 Buy
Biorbyt Ltd orb546156 1-EbIO >98% 50mg $304.3 2021-12-16 Buy

Properties

Melting point :118-120 °C(Solv: ethyl acetate (141-78-6))
Density :1.161±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: ≥20mg/mL
form :powder
pka :12.29±0.30(Predicted)
color :Crystalline
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

1-EBIO is an activator of Ca2+-sensitive K+ channels (EC50 = 490 μM in T84 human carcinoma cells). This action is sensitive to the neurotoxin charybdotoxin (Ki = 3.5 nM). In mouse colonic epithelia, 1-EBIO also activates cAMP-sensitive K+ channels, a response this is inhibited by 293B. In this type of epithelium, but not mouse nasal epithelia, 1-EBIO activates both types of channels, resulting in large Cl- secretory currents. It also activates the human intermediate conductance Ca2+-activated K+ channel (EC50 = 74 μM). 1-EBIO is currently used to study the role of these types of K+ channels in diverse physiological functions.

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