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ChemicalBook >> CAS DataBase List >> (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine price.
  • $32 - $606
  • Product name: (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine
  • CAS: 1000672-89-8
  • MF: C15H15ClN2
  • MW: 258.75
  • EINECS:
  • MDL Number:
  • Synonyms:(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine;Pyrazine, 2-[(1E)-2-(2-chlorophenyl)ethenyl]-3,5,6-trimethyl-;2-[(1E)-2-(2-chlorophenyl)ethenyl]-3,5,6-trimethyl-pyrazine
Price6 Properties Safety Information Description
6 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number3275DN
  • Product description2-[(E)-2-(2-Chlorophenyl)ethenyl]-3,5,6-trimethylpyrazine
  • Packaging5mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3275DN
  • Product description2-[(E)-2-(2-Chlorophenyl)ethenyl]-3,5,6-trimethylpyrazine
  • Packaging25mg
  • Price$606
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number9003202
  • Product description(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9003202
  • Product description(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine ≥98%
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9003202
  • Product description(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine ≥98%
  • Packaging10mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9003202
  • Product description(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine ≥98%
  • Packaging25mg
  • Price$456
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3275DN 2-[(E)-2-(2-Chlorophenyl)ethenyl]-3,5,6-trimethylpyrazine 5mg $226 2021-12-16 Buy
AK Scientific 3275DN 2-[(E)-2-(2-Chlorophenyl)ethenyl]-3,5,6-trimethylpyrazine 25mg $606 2021-12-16 Buy
Cayman Chemical 9003202 (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 9003202 (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine ≥98% 5mg $116 2024-03-01 Buy
Cayman Chemical 9003202 (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine ≥98% 10mg $214 2024-03-01 Buy
Cayman Chemical 9003202 (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine ≥98% 25mg $456 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 2 mg/ml; Ethanol: 2 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine (CSTMP) is a stilbene derivative with antioxidant and anticancer activities.1,2,3 It stimulates proliferation of hydrogen peroxide-damaged ECV-304 cells (EC50 = 24.9 nM).1 CSTMP reduces hydrogen peroxide-induced release of lactate dehydrogenase (LDH) in and increases viability of human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner via inhibition of apoptosis.2 It reverses hydrogen peroxide-induced release of malondialdehyde (MDA) and decreases in superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities as well as increases constitutive nitric oxide synthase (cNOS) activity and nitric oxide (NO) production in HUVECs. CSTMP also induces cell death of A549 non-small cell lung cancer (NSCLC) cells in an IRE1α-dependent manner through induction of IRE1α-TRAF2-ASK1 complex-mediated endoplasmic reticulum (ER) stress and mitochondrial apoptosis.3

Suppliers and manufacturers

TargetMol Chemicals Inc.
(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine
$78.00 /1mg
(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine CAS:1000672-89-8
Hangzhou MolCore BioPharmatech Co.,Ltd. Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. Shanghai Yifei Biotechnology Co. , Ltd. TargetMol Chemicals Inc.