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ChemicalBook >> CAS DataBase List >> (3aR,9bS)-6,8-difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline

(3aR,9bS)-6,8-difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline

(3aR,9bS)-6,8-difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline price.
10 prices
Selected condition:
Brand
  • AK Scientific
  • Biorbyt Ltd
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10μg
  • 5mg
  • 10mg
  • 25mg
  • 96Tests
  • ManufacturerAK Scientific
  • Product number9681CJ
  • Product description6,8-Difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
  • Packaging10mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb527874
  • Product descriptionGCA
  • Packaging10μg
  • Price$290.7
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18430
  • Product descriptionGolgicide A ≥98%
  • Packaging5mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18430
  • Product descriptionGolgicide A ≥98%
  • Packaging10mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18430
  • Product descriptionGolgicide A ≥98%
  • Packaging25mg
  • Price$278
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberG0923
  • Product descriptionGolgicide A ≥98% (HPLC)
  • Packaging5mg
  • Price$187
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberG0923
  • Product descriptionGolgicide A ≥98% (HPLC)
  • Packaging25mg
  • Price$679
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberG766510
  • Product descriptionrac-GolgicideA
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberG766510
  • Product descriptionrac-GolgicideA
  • Packaging25mg
  • Price$215
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number519255
  • Product descriptionGCA
  • Packaging96Tests
  • Price$729
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9681CJ 6,8-Difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline 10mg $232 2021-12-16 Buy
Biorbyt Ltd orb527874 GCA 10μg $290.7 2021-12-16 Buy
Cayman Chemical 18430 Golgicide A ≥98% 5mg $81 2024-03-01 Buy
Cayman Chemical 18430 Golgicide A ≥98% 10mg $120 2024-03-01 Buy
Cayman Chemical 18430 Golgicide A ≥98% 25mg $278 2024-03-01 Buy
Sigma-Aldrich G0923 Golgicide A ≥98% (HPLC) 5mg $187 2024-03-01 Buy
Sigma-Aldrich G0923 Golgicide A ≥98% (HPLC) 25mg $679 2024-03-01 Buy
TRC G766510 rac-GolgicideA 5mg $60 2021-12-16 Buy
TRC G766510 rac-GolgicideA 25mg $215 2021-12-16 Buy
Usbiological 519255 GCA 96Tests $729 2021-12-16 Buy

Properties

Boiling point :383.0±42.0 °C(Predicted)
Density :1.259±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: >10mg/mL
form :solid
pka :4.84±0.12(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ADP-ribosylation factor 1 (Arf1), when activated by guanine nucleotide exchange factors (ArfGEFs), plays a key role in regulating secretory traffic and membrane transport within the Golgi of eukaryotic cells. Golgicide A is a reversible inhibitor of the brefeldin A -resistant, cis-Golgi ArfGEF, GBF1 (IC50 = 3.3 μM). Inhibition of GBF1 via golgicide A can result in rapid dissociation of COPI vesicle coat protein from Golgi membranes and disassembly of the Golgi and trans-Golgi network. Golgicide A does not affect the association of the adaptor protein, AP-1, or the Arf1-binding protein, GCA3, with the trans-Golgi network nor does it interfere with the activity of the ArfGEFs, BIG1 or 2. Golgicide A can arrest the secretion of soluble and membrane-associated proteins at the ER-Golgi intermediate compartment, as well as prevent endocytic transport of Shiga toxin to the trans-Golgi network.