5-Methyl-N-phenyl-2-1H-pyridone-d5 ( Pirfenidone-d5 )
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- $106 - $1593.9
- Product name: 5-Methyl-N-phenyl-2-1H-pyridone-d5 ( Pirfenidone-d5 )
- CAS: 1020719-62-3
- MF: C12H11NO
- MW: 185.23
- EINECS:
- MDL Number:MFCD07369537
- Synonyms:5-Methyl-N-phenyl-2-1H-pyridone-d5 ( Pirfenidone-d5 );2(1H)-Pyridinone, 5-Methyl-1-phenyl-d5-;5-Methyl-1-(phenyl-2,3,4,5,6-d5)-2(1H)-pyridinone;Pirfenidone-d5Q: What is Pirfenidone-d5 Q: What is the CAS Number of Pirfenidone-d5 Q: What is the storage condition of Pirfenidone-d5 Q: What are the applications of Pirfenidone-d5;Pirfenidone-d5 (5-Methyl-N-Phenyl-2-1H-Pyridone-d5)?;2(1H)-Pyridinone, 5-methyl-1-(phenyl-2,3,4,5,6-d5)-;[2H5]-Pirfenidone;AMR69 D5
8 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- TRC
Package
- 500μg
- 1mg
- 5mg
- 10MG
- ManufacturerAK Scientific
- Product number8703DU
- Product description5-Methyl-N-phenyl-2-1H-pyridone-d5
- Packaging1mg
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberRDL0007218
- Product description5-METHYL-N-PHENYL-2-1H-PYRIDONE-D5 95.00%
- Packaging1MG
- Price$704.55
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberRDL0007218
- Product description5-METHYL-N-PHENYL-2-1H-PYRIDONE-D5 95.00%
- Packaging10MG
- Price$1593.9
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number26452
- Product descriptionPirfenidone-d5
- Packaging500μg
- Price$106
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number26452
- Product descriptionPirfenidone-d5
- Packaging1mg
- Price$178
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0019837
- Product descriptionPirfenidoneD5
- Packaging5mg
- Price$580
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0019837
- Product descriptionPirfenidoneD5
- Packaging10mg
- Price$1050
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberM325898
- Product description5-Methyl-N-phenyl-2-1H-pyridone-d5(Pirfenidone-d5)
- Packaging10mg
- Price$1230
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8703DU | 5-Methyl-N-phenyl-2-1H-pyridone-d5 | 1mg | $370 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0007218 | 5-METHYL-N-PHENYL-2-1H-PYRIDONE-D5 95.00% | 1MG | $704.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0007218 | 5-METHYL-N-PHENYL-2-1H-PYRIDONE-D5 95.00% | 10MG | $1593.9 | 2021-12-16 | Buy |
| Cayman Chemical | 26452 | Pirfenidone-d5 | 500μg | $106 | 2024-03-01 | Buy |
| Cayman Chemical | 26452 | Pirfenidone-d5 | 1mg | $178 | 2024-03-01 | Buy |
| ChemScene | CS-0019837 | PirfenidoneD5 | 5mg | $580 | 2021-12-16 | Buy |
| ChemScene | CS-0019837 | PirfenidoneD5 | 10mg | $1050 | 2021-12-16 | Buy |
| TRC | M325898 | 5-Methyl-N-phenyl-2-1H-pyridone-d5(Pirfenidone-d5) | 10mg | $1230 | 2021-12-16 | Buy |
Properties
Melting point :104-106°C
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), Ethanol, Ethyl Acetate, Methanol (Slightly)
form :Solid
color :White to Light Beige
InChI :InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
InChIKey :ISWRGOKTTBVCFA-UHFFFAOYSA-N
SMILES :O=C1C=CC(C)=CN1C1C([H])=C([H])C([H])=C([H])C=1[H]
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), Ethanol, Ethyl Acetate, Methanol (Slightly)
form :Solid
color :White to Light Beige
InChI :InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
InChIKey :ISWRGOKTTBVCFA-UHFFFAOYSA-N
SMILES :O=C1C=CC(C)=CN1C1C([H])=C([H])C([H])=C([H])C=1[H]
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Pirfenidone-d5 is intended for use as an internal standard for the quantification of pirfenidone by GC- or LC-MS. Pirfenidone is an orally bioavailable pyridone derivative with antifibrotic, anti-inflammatory, and antioxidant activities. It inhibits TGF-β1-stimulated increases in collagen type I, fibronectin, and Hsp47 expression in A549 lung cancer cells in a concentration-dependent manner. Pirfenidone (300 mg/kg per day) inhibits fibrosis and inhibits increases in collagen content, fibrocyte pool size, and the levels of chemokines CCL2 and CCL12 in lung in a mouse model of pulmonary fibrosis induced by bleomycin . In a mouse model of non-alcoholic steatohepatitis (NASH), pirfenidone inhibits fibrosis and increases in hepatocyte apoptosis, lobular inflammation, and hepatic expression of the fibrosis-related genes Col1a1, Timp1, Tgfb1, Pdgfb, and Fgf2 when administered at a dose of 280 mg/kg but has no effect on steatosis. Pirfenidone also inhibits NADPH-dependent lipid peroxidation in sheep liver microsomes and scavenges hydroxyl radicals (IC50s = ~6 and ~2.5 mM, respectively). Formulations containing pirfenidone have been used in the treatment of idiopathic pulmonary fibrosis.More related product prices
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