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ChemicalBook >> 1,2-Dibromoethane-1-sulfonyl fluoride

1,2-Dibromoethane-1-sulfonyl fluoride

1,2-Dibromoethane-1-sulfonyl fluoride price.
  • $228
  • Product name: 1,2-Dibromoethane-1-sulfonyl fluoride
  • CAS: 103020-97-9
  • MF: C2H3Br2FO2S
  • MW: 269.92
  • EINECS:
  • MDL Number:MFCD31615713
  • Synonyms:1,2-Dibromoethane-1-sulfonyl fluoride;Ethanesulfonyl fluoride, 1,2-dibromo-;1,2-dibromo-Ethanesulfonyl fluoride
1 prices
Selected condition:
Brand
  • Sigma-Aldrich
Package
  • 250mg
  • ManufacturerSigma-Aldrich
  • Product number906190
  • Product description1,2-Dibromoethane-1-sulfonyl fluoride
  • Packaging250mg
  • Price$228
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 906190 1,2-Dibromoethane-1-sulfonyl fluoride 250mg $228 2024-03-01 Buy

Properties

Boiling point :276.7±30.0 °C(Predicted)
Density :2.351±0.06 g/cm3(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

1,2-Dibromoethane-1-sulfonyl fluoride (DESF) is a bench-stable precursor to 1-bromoethene-1-sulfonyl fluoride (BESF), a new and robust connective hub for the Sulfur (VI) fluoride exchange (SuFEx) click reaction. BESF offers similar routes as ethenesulfonyl fluoride (ESF, cat# 746959) but with additional reactivity due to the embedded bromo group.

Treatment of DESF with triethylamine generates BESF in situ, which has been used to synthesize diverse and unprecented sulfonyl fluorides in good-to-excellent yields. As the resulting molecules possess sulfonyl fluoride handles, further SuFEx reactions are also possible. DESF adds another useful tool for conjugation strategies in chemical biology and organic and polymer synthesis.