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ChemicalBook >> CAS DataBase List >> N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methylbenzeneacetamide

N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methylbenzeneacetamide

N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methylbenzeneacetamide price.
  • $50 - $1600
  • Product name: N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methylbenzeneacetamide
  • CAS: 1105698-15-4
  • MF: C26H22N2O2
  • MW: 394.47
  • EINECS:
  • MDL Number:MFCD12912446
  • Synonyms:N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methylbenzeneacetamide;N-{3-[(2-Hydroxy-naphthalen-1-ylmethylene)-amino]-phenyl}-2-phenyl-propionamide;SIRT1/2 Inhibitor VIII, Salermide ;CS-2458;SIRT1/2 Inhibitor VIII, Salermide - CAS 1105698-15-4 - Calbiochem;N-[3-[[(2-HYDROXY-1-NAPHTHALENYL)METHYLENE]AMINO]PHENYL]-A-METHYL-BENZENEACETAMIDE;Benzeneacetamide, N-[3-[[(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methyl-;Salermide
29 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 5mg
  • 10mg
  • 25mg
  • 50
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2029AH
  • Product descriptionSalermide
  • Packaging100mg
  • Price$779
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA557147
  • Product descriptionN-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+%
  • Packaging5mg
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA557147
  • Product descriptionN-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+%
  • Packaging10mg
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA557147
  • Product descriptionN-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+%
  • Packaging25mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA557147
  • Product descriptionN-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+%
  • Packaging50mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7594
  • Product descriptionSalermide
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7594
  • Product descriptionSalermide
  • Packaging50mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2704
  • Product descriptionSalermide 99%
  • Packaging10mg
  • Price$104.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2704
  • Product descriptionSalermide 99%
  • Packaging50mg
  • Price$385
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545919
  • Product descriptionSalermide >98%
  • Packaging5mg
  • Price$154.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545919
  • Product descriptionSalermide >98%
  • Packaging25mg
  • Price$389.3
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13178
  • Product descriptionSalermide ≥98%
  • Packaging5mg
  • Price$50
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13178
  • Product descriptionSalermide ≥98%
  • Packaging10mg
  • Price$94
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13178
  • Product descriptionSalermide ≥98%
  • Packaging50mg
  • Price$389
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13178
  • Product descriptionSalermide ≥98%
  • Packaging100mg
  • Price$680
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6203
  • Product descriptionSalermide >98.0%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2029AH Salermide 100mg $779 2021-12-16 Buy
Ambeed A557147 N-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+% 5mg $51 2021-12-16 Buy
Ambeed A557147 N-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+% 10mg $67 2021-12-16 Buy
Ambeed A557147 N-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+% 25mg $88 2021-12-16 Buy
Ambeed A557147 N-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide 98+% 50mg $115 2021-12-16 Buy
ApexBio Technology B7594 Salermide 10mg $70 2021-12-16 Buy
ApexBio Technology B7594 Salermide 50mg $280 2021-12-16 Buy
Axon Medchem Axon2704 Salermide 99% 10mg $104.5 2021-12-16 Buy
Axon Medchem Axon2704 Salermide 99% 50mg $385 2021-12-16 Buy
Biorbyt Ltd orb545919 Salermide >98% 5mg $154.7 2021-12-16 Buy
Biorbyt Ltd orb545919 Salermide >98% 25mg $389.3 2021-12-16 Buy
Cayman Chemical 13178 Salermide ≥98% 5mg $50 2024-03-01 Buy
Cayman Chemical 13178 Salermide ≥98% 10mg $94 2024-03-01 Buy
Cayman Chemical 13178 Salermide ≥98% 50mg $389 2024-03-01 Buy
Cayman Chemical 13178 Salermide ≥98% 100mg $680 2024-03-01 Buy
ChemScene CS-6203 Salermide >98.0% 5mg $60 2021-12-16 Buy

Properties

Boiling point :666.7±50.0 °C(Predicted)
Density :1.16±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :Yellow solid
pka :7.90±0.50(Predicted)
color :Yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, or ethanol may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P321 Specific treatment (see … on this label).
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

The sirtuins (SIRTs) are a family of NAD+-dependent histone deacetylases involved in gene regulation that is relevant to, e.g., longevity, cancer, gene regulation, energy homeostasis, and apoptosis. Salermide is an inhibitor of SIRT1 and SIRT2, causing tumor-specific apoptotic cell death. In MOLT4 leukemia cells, salermide causes 90% apoptosis within 72 hours (IC50 ~ 20 μM) by reactivating proapototic genes that are repressed by SIRT1.

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