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ChemicalBook >> CAS DataBase List >> SB 290157 trifluoroacetate salt

SB 290157 trifluoroacetate salt

SB 290157 trifluoroacetate salt price.
  • $44 - $1400
  • Product name: SB 290157 trifluoroacetate salt
  • CAS: 1140525-25-2
  • MF: C24H29F3N4O6
  • MW: 526.51
  • EINECS:-0
  • MDL Number:MFCD04974198
  • Synonyms:SB 290157 trifluoroacetate salt;SB290157 (trifluoroacetate);SB 290157 TRIFLUOROACETATE; SB-290157 TRIFLUOROACETATE;SB 290157 - CAS 1140525-25-2 - Calbiochem;(2S)-5-(diaminomethylideneamino)-2-[[2-(2,2-diphenylethoxy)acetyl]amino]pentanoic acid;N2-(2-(2,2-diphenylethoxy)acetyl)-L-arginine, 2,2,2-trifluor;N2-(2-(2,2-diphenylethoxy)acetyl)-L-arginine (trifluoroacetate);SB290157,SB-290157 trifluoroacetate,Inhibitor,inhibit,SB 290157,Complement System,SB-290157,SB290157 trifluoroacetate
21 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number9488CW
  • Product descriptionSB290157(trifluoroacetate)
  • Packaging1mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3563
  • Product descriptionSB290157 trifluoroacetate salt
  • Packaging5mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3563
  • Product descriptionSB290157 trifluoroacetate salt
  • Packaging10mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3563
  • Product descriptionSB290157 trifluoroacetate salt
  • Packaging25mg
  • Price$327
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15783
  • Product descriptionSB 290157 (trifluoroacetate salt) ≥95%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15783
  • Product descriptionSB 290157 (trifluoroacetate salt) ≥95%
  • Packaging5mg
  • Price$87
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15783
  • Product descriptionSB 290157 (trifluoroacetate salt) ≥95%
  • Packaging10mg
  • Price$138
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15783
  • Product descriptionSB 290157 (trifluoroacetate salt) ≥95%
  • Packaging25mg
  • Price$288
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6852
  • Product descriptionSB290157(trifluoroacetate) 99.87%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6852
  • Product descriptionSB290157(trifluoroacetate) 99.87%
  • Packaging10mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6852
  • Product descriptionSB290157(trifluoroacetate) 99.87%
  • Packaging25mg
  • Price$204
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6852
  • Product descriptionSB290157(trifluoroacetate) 99.87%
  • Packaging50mg
  • Price$348
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6852
  • Product descriptionSB290157(trifluoroacetate) 99.87%
  • Packaging100mg
  • Price$612
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10151
  • Product descriptionSB290157trifluoroacetate >98%
  • Packaging100mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10151
  • Product descriptionSB290157trifluoroacetate >98%
  • Packaging250mg
  • Price$1400
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1192
  • Product descriptionSB290157 trifluoroacetate salt ≥97% (HPLC)
  • Packaging5mg
  • Price$103
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9488CW SB290157(trifluoroacetate) 1mg $147 2021-12-16 Buy
ApexBio Technology C3563 SB290157 trifluoroacetate salt 5mg $97 2021-12-16 Buy
ApexBio Technology C3563 SB290157 trifluoroacetate salt 10mg $154 2021-12-16 Buy
ApexBio Technology C3563 SB290157 trifluoroacetate salt 25mg $327 2021-12-16 Buy
Cayman Chemical 15783 SB 290157 (trifluoroacetate salt) ≥95% 1mg $44 2024-03-01 Buy
Cayman Chemical 15783 SB 290157 (trifluoroacetate salt) ≥95% 5mg $87 2024-03-01 Buy
Cayman Chemical 15783 SB 290157 (trifluoroacetate salt) ≥95% 10mg $138 2024-03-01 Buy
Cayman Chemical 15783 SB 290157 (trifluoroacetate salt) ≥95% 25mg $288 2024-03-01 Buy
ChemScene CS-6852 SB290157(trifluoroacetate) 99.87% 5mg $60 2021-12-16 Buy
ChemScene CS-6852 SB290157(trifluoroacetate) 99.87% 10mg $96 2021-12-16 Buy
ChemScene CS-6852 SB290157(trifluoroacetate) 99.87% 25mg $204 2021-12-16 Buy
ChemScene CS-6852 SB290157(trifluoroacetate) 99.87% 50mg $348 2021-12-16 Buy
ChemScene CS-6852 SB290157(trifluoroacetate) 99.87% 100mg $612 2021-12-16 Buy
DC Chemicals DC10151 SB290157trifluoroacetate >98% 100mg $700 2021-12-16 Buy
DC Chemicals DC10151 SB290157trifluoroacetate >98% 250mg $1400 2021-12-16 Buy
Sigma-Aldrich SML1192 SB290157 trifluoroacetate salt ≥97% (HPLC) 5mg $103 2024-03-01 Buy

Properties

Melting point :>43°C (dec.)
storage temp. :-20°C
solubility :Ethanol (Slightly, Sonicated), Methanol (Slightly), Water (Slightly)
form :powder
color :white to beige
optical activity :[α]/D +1.5 to +5°, c = 1.0 in DMSO
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The anaphylatoxin C3a induces a range of responses by activating its G protein-coupled receptor, C3aR, resulting in calcium mobilization. SB 290157 is a non-peptide antagonist of C3aR, competitively blocking C3a binding with an IC50 value of 200 nM. It potently inhibits a wide variety of C3a-induced responses in cells, including calcium increase in human neutrophils (IC50 = 28 nM) and ATP release from guinea pig platelets (IC50 = 30 nM). SB 290157 is also effective in vivo, reducing inflammation in a variety of animal models. It also significantly reduces or reverses diet-induced obesity in rats and accelerates the mobilization of hematopoietic progenitor cells to the peripheral blood in mice. Notably, SB 290157 has C3aR agonist activity in some cell systems.