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ChemicalBook >> CAS DataBase List >> 14,15-DEHYDRO LEUKOTRIENE B4

14,15-DEHYDRO LEUKOTRIENE B4

14,15-DEHYDRO LEUKOTRIENE B4 price.
  • $138 - $491
  • Product name: 14,15-DEHYDRO LEUKOTRIENE B4
  • CAS: 114616-11-4
  • MF: C20H30O4
  • MW: 334.45
  • EINECS:
  • MDL Number:MFCD00210857
  • Synonyms:14,15-DEHYDRO LEUKOTRIENE B4;5S,12R-DIHYDROXY-6Z,8E,10E-EICOSATRIEN-14-YNOIC ACID;PRCVOEPTHWOJMX-CHHAPGPYSA-N;6,8,10-Eicosatrien-14-ynoic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R)-;(5S,6Z,8E,10E,12R)-5,12-Dihydroxyicosa-6,8,10-trien-14-ynoic acid;14,15 dehydro Leukotriene B4,14,15-dehydro Leukotriene B-4,14,15dehydro Leukotriene B4
4 prices
Selected condition:
Brand
  • Cayman Chemical
  • TRC
Package
  • 25μg
  • 50μg
  • 100μg
  • ManufacturerCayman Chemical
  • Product number20150
  • Product description14,15-dehydro Leukotriene B4 ≥97%
  • Packaging25μg
  • Price$138
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20150
  • Product description14,15-dehydro Leukotriene B4 ≥97%
  • Packaging50μg
  • Price$261
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20150
  • Product description14,15-dehydro Leukotriene B4 ≥97%
  • Packaging100μg
  • Price$491
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberL330365
  • Product description14,15-dehydroLeukotrieneB4
  • Packaging50μg
  • Price$185
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 20150 14,15-dehydro Leukotriene B4 ≥97% 25μg $138 2024-03-01 Buy
Cayman Chemical 20150 14,15-dehydro Leukotriene B4 ≥97% 50μg $261 2024-03-01 Buy
Cayman Chemical 20150 14,15-dehydro Leukotriene B4 ≥97% 100μg $491 2024-03-01 Buy
TRC L330365 14,15-dehydroLeukotrieneB4 50μg $185 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): >1 mg/ml

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. At least two LTB4 receptors, termed BLT1 and BLT2, have been identified. 14,15-dehydro LTB4 is a LTB4 receptor antagonist that has a higher binding affinity for BLT1, demonstrating a Ki value of 27 nM, compared to BLT2, which has a Ki value of 473 nM. 14,15-dehydro LTB4 inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC50 value of 1 μM.

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