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ChemicalBook >> CAS DataBase List >> D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide

D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide

D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide price.
  • $242 - $347
  • Product name: D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide
  • CAS: 1173671-63-0
  • MF: C20H18N6O
  • MW: 358.4
  • EINECS:
  • MDL Number:MFCD04006470
  • Synonyms:D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide;Rhosin;Rhosin /G04, (2R)-2-Amino-3-(1H-indol-3-yl)-N′-((1E)-quinoxalin-6-ylmethylidene)propanehydrazide;Rho Inhibitor, Rhosin - Calbiochem;Rhosin (G04)
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • Crysdot
  • CSNpharm
  • Sigma-Aldrich
Package
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerCrysdot
  • Product numberCD31004418
  • Product descriptionRhosin 98+%
  • Packaging5mg
  • Price$243
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004418
  • Product descriptionRhosin 98+%
  • Packaging10mg
  • Price$347
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN17515
  • Product descriptionRhosin
  • Packaging5mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number555460-M
  • Product descriptionRho Inhibitor, Rhosin - Calbiochem
  • Packaging25mg
  • Price$242
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Crysdot CD31004418 Rhosin 98+% 5mg $243 2021-12-16 Buy
Crysdot CD31004418 Rhosin 98+% 10mg $347 2021-12-16 Buy
CSNpharm CSN17515 Rhosin 5mg $336 2021-12-16 Buy
Sigma-Aldrich 555460-M Rho Inhibitor, Rhosin - Calbiochem 25mg $242 2024-03-01 Buy

Properties

Density :1.38±0.1 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :Soluble in DMSO
form :Orange brown powder
pka :12.00±0.46(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ChEBI: Rhosin is a D-tryptophan derivative obtained by formal condensation of the carboxy group of D-tryptophan with the amino group of (quinoxalin-6-yl)methylidenehydrazide. It directly targets the Rho GEF binding domain, thereby preventing Rho from interacting with its GEFs It has a role as a RhoA inhibitor, a RhoC inhibitor and an antineoplastic agent. It is a D-tryptophan derivative, a quinoxaline derivative and a hydrazone.

Suppliers and manufacturers

TargetMol Chemicals Inc.
Zibo Hangyu Biotechnology Development Co., Ltd Sichuan Wei Keqi Biological Technology Co., Ltd. LETOPHARM LIMITED BOC Sciences Shanghai Rechem science Co., Ltd. Musechem Fan De(Beijing) Biotechnology Co., Ltd. Absin Bioscience Inc. Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd