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ChemicalBook >> CAS DataBase List >> N-((1-(2-(tert-ButylaMino)-2-oxoethyl)piperidin-4-yl)Methyl)-3-chloro-5-fluorobenzaMide

N-((1-(2-(tert-ButylaMino)-2-oxoethyl)piperidin-4-yl)Methyl)-3-chloro-5-fluorobenzaMide

N-((1-(2-(tert-ButylaMino)-2-oxoethyl)piperidin-4-yl)Methyl)-3-chloro-5-fluorobenzaMide price.
  • $32 - $2620
  • Product name: N-((1-(2-(tert-ButylaMino)-2-oxoethyl)piperidin-4-yl)Methyl)-3-chloro-5-fluorobenzaMide
  • CAS: 1199236-64-0
  • MF: C19H27ClFN3O2
  • MW: 383.89
  • EINECS:
  • MDL Number:MFCD27966181
  • Synonyms:4-[[(3-Chloro-5-fluorobenzoyl)aMino]Methyl]-N-(1,1-diMethylethyl)-1-piperidineacetaMide;N-((1-(2-(tert-ButylaMino)-2-oxoethyl)piperidin-4-yl)Methyl)-3-chloro-5-fluorobenzaMide;Z-944;1-Piperidineacetamide, 4-[[(3-chloro-5-fluorobenzoyl)amino]methyl]-N-(1,1-dimethylethyl)-;N-[[1-[2-(tert-butylamino)-2-;Ca channels,Inhibitor,Calcium Channel,Ca2+ channels,Z944,inhibit;Ulixacaltamide (Z944);Ulixacaltamide
9 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • Tocris
Package
  • 10
  • 1mg
  • 5MG
  • 50
  • 10mg
  • 25mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number3396DF
  • Product descriptionN-((1-(2-(Tert-Butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0371140
  • Product descriptionN-((1-(2-(TERT-BUTYLAMINO)-2-OXOETHYL)PIPERIDIN-4-YL)METHYL)-3-CHLORO-5-FLUOROBENZAMIDE 95.00%
  • Packaging5MG
  • Price$504.67
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27679
  • Product descriptionZ944
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27679
  • Product descriptionZ944
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27679
  • Product descriptionZ944
  • Packaging10mg
  • Price$243
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27679
  • Product descriptionZ944
  • Packaging25mg
  • Price$571
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number21541
  • Product descriptionN-((1-(2-(tert-Butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide
  • Packaging100mg
  • Price$2620
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number6367
  • Product descriptionZ944 ≥98%(HPLC)
  • Packaging10
  • Price$223
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number6367
  • Product descriptionZ944 ≥98%(HPLC)
  • Packaging50
  • Price$936
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3396DF N-((1-(2-(Tert-Butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide 1mg $133 2021-12-16 Buy
American Custom Chemicals Corporation HCH0371140 N-((1-(2-(TERT-BUTYLAMINO)-2-OXOETHYL)PIPERIDIN-4-YL)METHYL)-3-CHLORO-5-FLUOROBENZAMIDE 95.00% 5MG $504.67 2021-12-16 Buy
Cayman Chemical 27679 Z944 1mg $32 2024-03-01 Buy
Cayman Chemical 27679 Z944 5mg $139 2024-03-01 Buy
Cayman Chemical 27679 Z944 10mg $243 2024-03-01 Buy
Cayman Chemical 27679 Z944 25mg $571 2024-03-01 Buy
Medical Isotopes, Inc. 21541 N-((1-(2-(tert-Butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide 100mg $2620 2021-12-16 Buy
Tocris 6367 Z944 ≥98%(HPLC) 10 $223 2021-12-16 Buy
Tocris 6367 Z944 ≥98%(HPLC) 50 $936 2021-12-16 Buy

Properties

Melting point :122-124°C
Boiling point :528.1±50.0 °C(Predicted)
Density :1.166±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :13.65±0.46(Predicted)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Z944 is an inhibitor of T-type calcium channels (IC50s = 0.050-0.160 μM for the human recombinant voltage-gated calcium (Cav) channels Cav3.1, Cav3.2, and Cav3.3). It is selective for T-type channels over the N-type Cav2.2 channel (IC50 = 11 μM), as well as the rat L-type Cav1.2, human-ether-a-go-go (hERG/Kv11.1) potassium, and human voltage-gated sodium (Nav) channel Nav1.5 (IC50s = 32, 7.8, and 100 μM, respectively). Z944 (30 mg/kg) reduces the seizure duration and the amount of time rats spend in seizures in a model of absence epilepsy. It delays seizure progression in amygdala-kindled rats but does not inhibit seizures in fully kindled rats.