(±)12,13-DiHOME
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- $32 - $1110
- Product name: (±)12,13-DiHOME
- CAS: 263399-35-5
- MF: C18H34O4
- MW: 314.46
- EINECS:
- MDL Number:MFCD12912337
- Synonyms:(±)12,13-DiHOME;9-Octadecenoic acid, 12,13-dihydroxy-, (9Z)-;(±)12(13)-DiHOME MaxSpec Standard
6 prices
Selected condition：
Brand
- Cayman Chemical
- TRC
Package
- 25μg
- 50μg
- 100μg
- 500μg
- 1mg
- 5mg
- ManufacturerCayman Chemical
- Product number10009832
- Product description(±)12(13)-DiHOME ≥98%
- Packaging500μg
- Price$486
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10009832
- Product description(±)12(13)-DiHOME ≥98%
- Packaging100μg
- Price$111
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10009832
- Product description(±)12(13)-DiHOME ≥98%
- Packaging50μg
- Price$61
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10009832
- Product description(±)12(13)-DiHOME ≥98%
- Packaging25μg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberD679053
- Product description(±)-12,13-DIHOME
- Packaging1mg
- Price$265
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberD679053
- Product description(±)-12,13-DIHOME
- Packaging5mg
- Price$1110
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 10009832 | (±)12(13)-DiHOME ≥98% | 500μg | $486 | 2024-03-01 | Buy |
| Cayman Chemical | 10009832 | (±)12(13)-DiHOME ≥98% | 100μg | $111 | 2024-03-01 | Buy |
| Cayman Chemical | 10009832 | (±)12(13)-DiHOME ≥98% | 50μg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 10009832 | (±)12(13)-DiHOME ≥98% | 25μg | $32 | 2024-03-01 | Buy |
| TRC | D679053 | (±)-12,13-DIHOME | 1mg | $265 | 2021-12-16 | Buy |
| TRC | D679053 | (±)-12,13-DIHOME | 5mg | $1110 | 2021-12-16 | Buy |
Properties
Boiling point :476.0±30.0 °C(Predicted)
Density :1.015±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml,PBS (pH 7.2): 10 μ g/ml
pka :4.78±0.10(Predicted)
form :Liquid
color :Colorless to light yellow
Density :1.015±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml,PBS (pH 7.2): 10 μ g/ml
pka :4.78±0.10(Predicted)
form :Liquid
color :Colorless to light yellow
Safety Information
| Symbol(GHS): |
 
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Description
(±)12,13-DiHOME is the diol resulting from the soluble epoxide hydrolase opening of (±)12,13-EpOME. The mixture of the methyl ester of this diol and the 9,10 isomer are more cytotoxic than the methyl ester epoxides in renal proximal tubular cells.However, in renal cortical mitochondria, the conversion of the epoxide to 12,13-DiHOME appears to be part of the detoxification pathway that prevents mitochondrial dysfunction. This diol and the 9,10 isomer can be glucuronidated by human liver and intestinal microsomes as well as recombinant UGT2B7 through a hydroxyl group. High levels of LA-diol glucuronides have been found in the urine of humans with peroxisomal diseases. A mixture of the diols stimulates breast cancer cell proliferation in vitro and disrupts reproductive function in rats at relatively low concentrations.Suppliers and manufacturers
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