N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
- $33 - $1800
- Product name: N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
- CAS: 1207360-89-1
- MF: C24H32N6O3
- MW: 452.55
- EINECS:200-258-5
- MDL Number:MFCD22417087
- Synonyms:GDC-0349;N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea;RG-7603;Urea, N-ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]-;GDC-0349 N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea;(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea;(S)-1-Ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimi;CS-695
18 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 500μg
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 250mg
- 10mM(in 1mL DMSO)
- 100mg
- ManufacturerAK Scientific
- Product number2427AH
- Product description1-Ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
- Packaging25mg
- Price$779
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2427AH
- Product description1-Ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
- Packaging10mg
- Price$414
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0017259
- Product descriptionGDC-0349 95.00%
- Packaging5MG
- Price$381.7
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1642
- Product description1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1642
- Product description1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
- Packaging10mM(in 1mL DMSO)
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1642
- Product description1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
- Packaging25mg
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1642
- Product description1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
- Packaging100mg
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number24058
- Product descriptionGDC-0349 ≥98%
- Packaging500μg
- Price$33
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24058
- Product descriptionGDC-0349 ≥98%
- Packaging1mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24058
- Product descriptionGDC-0349 ≥98%
- Packaging5mg
- Price$238
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24058
- Product descriptionGDC-0349 ≥98%
- Packaging10mg
- Price$443
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0700
- Product descriptionGDC-0349 98.20%
- Packaging5mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0700
- Product descriptionGDC-0349 98.20%
- Packaging10mg
- Price$216
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0700
- Product descriptionGDC-0349 98.20%
- Packaging50mg
- Price$948
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004284
- Product descriptionGDC-0349 98+%
- Packaging5mg
- Price$77
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004284
- Product descriptionGDC-0349 98+%
- Packaging10mg
- Price$140
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2427AH | 1-Ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea | 25mg | $779 | 2021-12-16 | Buy |
AK Scientific | 2427AH | 1-Ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea | 10mg | $414 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0017259 | GDC-0349 95.00% | 5MG | $381.7 | 2021-12-16 | Buy |
ApexBio Technology | A1642 | 1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea | 5mg | $120 | 2021-12-16 | Buy |
ApexBio Technology | A1642 | 1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea | 10mM(in 1mL DMSO) | $120 | 2021-12-16 | Buy |
ApexBio Technology | A1642 | 1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea | 25mg | $480 | 2021-12-16 | Buy |
ApexBio Technology | A1642 | 1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea | 100mg | $1200 | 2021-12-16 | Buy |
Cayman Chemical | 24058 | GDC-0349 ≥98% | 500μg | $33 | 2024-03-01 | Buy |
Cayman Chemical | 24058 | GDC-0349 ≥98% | 1mg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 24058 | GDC-0349 ≥98% | 5mg | $238 | 2024-03-01 | Buy |
Cayman Chemical | 24058 | GDC-0349 ≥98% | 10mg | $443 | 2024-03-01 | Buy |
ChemScene | CS-0700 | GDC-0349 98.20% | 5mg | $132 | 2021-12-16 | Buy |
ChemScene | CS-0700 | GDC-0349 98.20% | 10mg | $216 | 2021-12-16 | Buy |
ChemScene | CS-0700 | GDC-0349 98.20% | 50mg | $948 | 2021-12-16 | Buy |
Crysdot | CD31004284 | GDC-0349 98+% | 5mg | $77 | 2021-12-16 | Buy |
Crysdot | CD31004284 | GDC-0349 98+% | 10mg | $140 | 2021-12-16 | Buy |
Properties
Boiling point :571.3±50.0 °C(Predicted)
Density :1.269
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:9): 0.1 mg/ml; Ethanol: 10 mg/ml
form :Powder
pka :13.87±0.46(Predicted)
color :Light yellow to yellow
Density :1.269
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:9): 0.1 mg/ml; Ethanol: 10 mg/ml
form :Powder
pka :13.87±0.46(Predicted)
color :Light yellow to yellow
Safety Information
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Description
N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea is a potent and selective mTOR inhibitor with dose-dependent efficacy in mouse x enograft cancer models.More related product prices
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