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ChemicalBook >> CAS DataBase List >> 9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC-17,17,18,18,19,19-D6 ACID

9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC-17,17,18,18,19,19-D6 ACID

9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC-17,17,18,18,19,19-D6 ACID price.
3 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 25μg
  • 50μg
  • 100μg
  • ManufacturerCayman Chemical
  • Product number314840
  • Product descriptiontetranor-PGEM-d6 ≥99% deuterated forms (may contain d4-d8)
  • Packaging25μg
  • Price$267
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number314840
  • Product descriptiontetranor-PGEM-d6 ≥99% deuterated forms (may contain d4-d8)
  • Packaging50μg
  • Price$505
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number314840
  • Product descriptiontetranor-PGEM-d6 ≥99% deuterated forms (may contain d4-d8)
  • Packaging100μg
  • Price$957
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 314840 tetranor-PGEM-d6 ≥99% deuterated forms (may contain d4-d8) 25μg $267 2024-03-01 Buy
Cayman Chemical 314840 tetranor-PGEM-d6 ≥99% deuterated forms (may contain d4-d8) 50μg $505 2024-03-01 Buy
Cayman Chemical 314840 tetranor-PGEM-d6 ≥99% deuterated forms (may contain d4-d8) 100μg $957 2024-03-01 Buy

Properties

storage temp. :Store at -80°C
solubility :DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: Not Stable,PBS (pH 7.2): 1 mg/ml
form :Liquid
color :Colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Tetranor prostaglandin E metabolite-d6 (tetranor-PGEM-d6) contains six deuterium atoms at the 13, 13, 14, 14, 15, and 15 positions. It is intended for use as an internal standard for the quantification of tetranor PGEM by GC- or LC-mass spectrometry. Tetranor PGEM-d6 is the major urinary metabolite of PGE1 and PGE2. It is used as a urinary marker of PGE2 biosynthesis, and to monitor metabolism after infusion or injection of PGE1 as a pharmaceutical. Normal healthy males excrete 16-30 μg of tetranor PGEM over a 24-hour period. Females excrete less by about a factor of three. Following oral administration (4 x 50 mg/24 hours) of the COX inhibitor, indomethacin, urinary levels of tetranor PGEM decrease by 75-98% indicating the almost complete loss of PGE2 biosynthesis.