3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine
![3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine price.](/CAS/GIF/1254977-87-1.gif)
|
- $37 - $2000
- Product name: 3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine
- CAS: 1254977-87-1
- MF: C22H23F3N4
- MW: 400.44
- EINECS:
- MDL Number:MFCD22199231
- Synonyms:3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine;JNJ42153605 (on going);JNJ-42153605;JNJ42153605;CS-2446;3-(Cyclopropylmethyl)-7-(4-phenyl-1-piperidinyl)-8-(trifluorometh yl)[1,2,4]triazolo[4,3-a]pyridine;1,2,4-Triazolo[4,3-a]pyridine, 3-(cyclopropylmethyl)-7-(4-phenyl-1-piperidinyl)-8-(trifluoromethyl)-;Inhibitor,JNJ42153605,Metabotropic glutamate receptors,JNJ-42153605,inhibit,JNJ 42153605,mGluR
11 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number3032DH
- Product description3-(Cyclopropylmethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
- Packaging1mg
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21984
- Product descriptionJNJ-42153605
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21984
- Product descriptionJNJ-42153605
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21984
- Product descriptionJNJ-42153605
- Packaging10mg
- Price$283
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21984
- Product descriptionJNJ-42153605
- Packaging25mg
- Price$618
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-6317
- Product descriptionJNJ-42153605 99.00%
- Packaging5mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6317
- Product descriptionJNJ-42153605 99.00%
- Packaging10mg
- Price$264
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6317
- Product descriptionJNJ-42153605 99.00%
- Packaging50mg
- Price$792
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6317
- Product descriptionJNJ-42153605 99.00%
- Packaging100mg
- Price$1140
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7843
- Product descriptionJNJ42153605 >98%
- Packaging250mg
- Price$1000
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7843
- Product descriptionJNJ42153605 >98%
- Packaging1g
- Price$2000
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3032DH | 3-(Cyclopropylmethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine | 1mg | $139 | 2021-12-16 | Buy |
| Cayman Chemical | 21984 | JNJ-42153605 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 21984 | JNJ-42153605 | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 21984 | JNJ-42153605 | 10mg | $283 | 2024-03-01 | Buy |
| Cayman Chemical | 21984 | JNJ-42153605 | 25mg | $618 | 2024-03-01 | Buy |
| ChemScene | CS-6317 | JNJ-42153605 99.00% | 5mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-6317 | JNJ-42153605 99.00% | 10mg | $264 | 2021-12-16 | Buy |
| ChemScene | CS-6317 | JNJ-42153605 99.00% | 50mg | $792 | 2021-12-16 | Buy |
| ChemScene | CS-6317 | JNJ-42153605 99.00% | 100mg | $1140 | 2021-12-16 | Buy |
| DC Chemicals | DC7843 | JNJ42153605 >98% | 250mg | $1000 | 2021-12-16 | Buy |
| DC Chemicals | DC7843 | JNJ42153605 >98% | 1g | $2000 | 2021-12-16 | Buy |
Properties
Density :1.38±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF:30.0(Max Conc. mg/mL);74.92(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.62(Max Conc. mM)
DMSO:10.34(Max Conc. mg/mL);25.81(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);24.97(Max Conc. mM) form :A crystalline solid
pka :3.07±0.30(Predicted)
color :White to off-white
storage temp. :Store at -20°C
solubility :DMF:30.0(Max Conc. mg/mL);74.92(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.62(Max Conc. mM)
DMSO:10.34(Max Conc. mg/mL);25.81(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);24.97(Max Conc. mM) form :A crystalline solid
pka :3.07±0.30(Predicted)
color :White to off-white
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
JNJ-42153605 is a positive allosteric modulator of metabotropic glutamate receptor 2 (mGluR2; EC50 = 17 nM in CHO cells expressing the human receptor). In vivo, JNJ-42153605 (3 mg/kg) inhibits mGluR2-mediated rapid eye movement (REM) sleep in rats. It also reverses phencyclidine-induced hyperlocomotion in mice (ED50 = 5.4 mg/kg).Related product price
- 2-(4-Chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide
$110-2600 - JNJ-632
$44-2900 - JNJ 31020028
$68-1900
Suppliers and manufacturers
career henan chemical co
![3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine](https://img.chemicalbook.com/ProductImageEN/2020-1/small/01c68305-6822-461f-8b31-b6743bbbf4d1.jpg)
ATK CHEMICAL COMPANY LIMITED
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Hangzhou MolCore BioPharmatech Co.,Ltd.
TargetMol Chemicals Inc.
Aladdin Scientific
Shanghai Boc Chemical Co.,Ltd
shanghai cooperpharm co.,LTD .
AdooQ BioScience, LLC
$2.00 /1KG
3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine CAS: 1254977-87-1
3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine CAS: 1254977-87-1