4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide
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- $38 - $1200
- Product name: 4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide
- CAS: 1261576-81-1
- MF: C25H24ClN3O3S2
- MW: 514.06
- EINECS:
- MDL Number:
- Synonyms:4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide;B355252;2-Thiophenesulfonamide, 4-chloro-N-(1-naphthalenylmethyl)-5-[3-(1-piperazinyl)phenoxy]-;B355252 >=98% (HPLC);4-chloro-N-(1-naphthalenylmethyl)-5-[3-(1-piperazinyl)phenoxy]-2-thiophenesulfonamide;neurite outgrowth,ischemic neurons,HT22,B355252,glutamate,Inhibitor,Apoptosis,DNA damage,inhibit,B 355252,NGF,LDH level,ROS production,Parkinson disease,phenoxy thiophene sulfonamide,B-355252
11 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- ManufacturerAK Scientific
- Product number1220DJ
- Product description4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide
- Packaging10mg
- Price$167
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21550
- Product descriptionB355252
- Packaging5mg
- Price$38
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21550
- Product descriptionB355252
- Packaging10mg
- Price$63
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21550
- Product descriptionB355252
- Packaging25mg
- Price$146
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21550
- Product descriptionB355252
- Packaging50mg
- Price$257
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC32427
- Product descriptionB355252
- Packaging100mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC32427
- Product descriptionB355252
- Packaging250mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC32427
- Product descriptionB355252
- Packaging1G
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1007
- Product descriptionB355252 ≥98% (HPLC)
- Packaging10mg
- Price$65.3
- Updated2022-05-15
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1007
- Product descriptionB355252 ≥98% (HPLC)
- Packaging50mg
- Price$445
- Updated2023-06-20
- Buy
- ManufacturerTRC
- Product numberB999588
- Product description4-Chloro-N-(1-naphthalenylmethyl)-5-[3-(1-piperazinyl)phenoxy]-2-thiophenesulfonamide
- Packaging2mg
- Price$65
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1220DJ | 4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide | 10mg | $167 | 2021-12-16 | Buy |
| Cayman Chemical | 21550 | B355252 | 5mg | $38 | 2024-03-01 | Buy |
| Cayman Chemical | 21550 | B355252 | 10mg | $63 | 2024-03-01 | Buy |
| Cayman Chemical | 21550 | B355252 | 25mg | $146 | 2024-03-01 | Buy |
| Cayman Chemical | 21550 | B355252 | 50mg | $257 | 2024-03-01 | Buy |
| DC Chemicals | DC32427 | B355252 | 100mg | $350 | 2021-12-16 | Buy |
| DC Chemicals | DC32427 | B355252 | 250mg | $600 | 2021-12-16 | Buy |
| DC Chemicals | DC32427 | B355252 | 1G | $1200 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML1007 | B355252 ≥98% (HPLC) | 10mg | $65.3 | 2022-05-15 | Buy |
| Sigma-Aldrich | SML1007 | B355252 ≥98% (HPLC) | 50mg | $445 | 2023-06-20 | Buy |
| TRC | B999588 | 4-Chloro-N-(1-naphthalenylmethyl)-5-[3-(1-piperazinyl)phenoxy]-2-thiophenesulfonamide | 2mg | $65 | 2021-12-16 | Buy |
Properties
Melting point :142-144 °C
Boiling point :718.4±70.0 °C(Predicted)
Density :1.370±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
pka :10.16±0.50(Predicted)
color :white to beige
Boiling point :718.4±70.0 °C(Predicted)
Density :1.370±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
pka :10.16±0.50(Predicted)
color :white to beige
Safety Information
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Description
B355252 is a neuroprotective agent. It potentiates NGF-induced neurite outgrowth in NS-1 cells (EC50 = ~1 μM). B355252 inhibits glutamate-induced excitotoxicity in HT-22 cells in a concentration-dependent manner and inhibits glutamate-induced decreases in GSH levels and increases in Bax levels, intracellular accumulation of calcium, and production of reactive oxygen species (ROS) in HT-22 cells when used at a concentration of 8 μM. It also inhibits decreases in cell viability, increases in ROS production, and mitochondrial membrane depolarization induced by 6-hydroxydopamine (6-OHDA; ) in HT-22 cells, an in vitro model of Parkinson’s disease.Suppliers and manufacturers
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