Welcome to chemicalbook!

400-158-6606

18162-48-6 872-50-4 Methylene Chloride naphthalene THF Titanium Dioxide

Structure Search

Inquriy

Try our best to find the right business for you.

Messages

Do not miss inquiry messages Please log in to view all inquiry messages.

My chemicalbook

Welcome back!

ChemicalBook >> CAS DataBase List >> 6-(2-Chloro-4-thiazol-5-yl-phenyl)-8-ethyl-2-[4-(4-Methyl-piperazin-1-yl)-phenylaMino]-8H-pyrido[2,3-d]pyriMidin-7-one

6-(2-Chloro-4-thiazol-5-yl-phenyl)-8-ethyl-2-[4-(4-Methyl-piperazin-1-yl)-phenylaMino]-8H-pyrido[2,3-d]pyriMidin-7-one

$37 - $2500
Product name: 6-(2-Chloro-4-thiazol-5-yl-phenyl)-8-ethyl-2-[4-(4-Methyl-piperazin-1-yl)-phenylaMino]-8H-pyrido[2,3-d]pyriMidin-7-one
CAS: 1286739-19-2
MF: C29H28ClN7OS
MW: 558.1
EINECS:-0
MDL Number:MFCD25976723
Synonyms:6-(2-Chloro-4-thiazol-5-yl-phenyl)-8-ethyl-2-[4-(4-Methyl-piperazin-1-yl)-phenylaMino]-8H-pyrido[2,3-d]pyriMidin-7-one;FRAX597;Pyrido[2,3-d]pyriMidin-7(8H)-one, 6-[2-chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-Methyl-1-piperazinyl)phenyl]aMino]-;6-(2-chloro-4-(thiazol-5-yl)phenyl)-8-ethyl-2-(4-(4-methylpiperazin-1-yl)phenylamino)pyrido[2,3-d]pyrimidin-7(8H)-one;6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one;FRAX597, >=98%;6-(2-Chloro-4-thiazol-5-yl-phenyl)-8-ethyl-2-[4-(4-Methyl-piperazin-1-yl)-phenylaMino]-8H-pyrido[2,3-d]pyriMidin-7-one USP/EP/BP;6-[2-chloro-4-(1,3-thiazol-5-yl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one

Price31 Properties Safety Information Description

31 prices

Selected condition：

Brand

AK Scientific
Ambeed
ApexBio Technology
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
Sigma-Aldrich
Tocris
TRC
Usbiological

Package

10mM(in 1mL DMSO)
10
1mg
2mg
5mg
50
10mg
25mg
50mg
100mg
250mg
1g

ManufacturerAK Scientific
Product number2182DU
Product descriptionCID70934541
Packaging1mg
Price$140
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2182DU
Product descriptionCID70934541
Packaging5mg
Price$282
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA123005
Product descriptionFRAX597 98+%
Packaging2mg
Price$37
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA123005
Product descriptionFRAX597 98+%
Packaging5mg
Price$72
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA123005
Product descriptionFRAX597 98+%
Packaging10mg
Price$108
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA123005
Product descriptionFRAX597 98+%
Packaging25mg
Price$140
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA123005
Product descriptionFRAX597 98+%
Packaging50mg
Price$182
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA123005
Product descriptionFRAX597 98+%
Packaging100mg
Price$323
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA123005
Product descriptionFRAX597 98+%
Packaging250mg
Price$645
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB1162
Product descriptionFRAX597
Packaging5mg
Price$120
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB1162
Product descriptionFRAX597
Packaging10mM(in 1mL DMSO)
Price$147
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB1162
Product descriptionFRAX597
Packaging25mg
Price$390
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number22205
Product descriptionFRAX597 ≥98%
Packaging1mg
Price$38
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number22205
Product descriptionFRAX597 ≥98%
Packaging5mg
Price$166
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number22205
Product descriptionFRAX597 ≥98%
Packaging10mg
Price$238
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number22205
Product descriptionFRAX597 ≥98%
Packaging25mg
Price$547
Updated2024-03-01
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	2182DU	CID70934541	1mg	$140	2021-12-16	Buy
AK Scientific	2182DU	CID70934541	5mg	$282	2021-12-16	Buy
Ambeed	A123005	FRAX597 98+%	2mg	$37	2021-12-16	Buy
Ambeed	A123005	FRAX597 98+%	5mg	$72	2021-12-16	Buy
Ambeed	A123005	FRAX597 98+%	10mg	$108	2021-12-16	Buy
Ambeed	A123005	FRAX597 98+%	25mg	$140	2021-12-16	Buy
Ambeed	A123005	FRAX597 98+%	50mg	$182	2021-12-16	Buy
Ambeed	A123005	FRAX597 98+%	100mg	$323	2021-12-16	Buy
Ambeed	A123005	FRAX597 98+%	250mg	$645	2021-12-16	Buy
ApexBio Technology	B1162	FRAX597	5mg	$120	2021-12-16	Buy
ApexBio Technology	B1162	FRAX597	10mM(in 1mL DMSO)	$147	2021-12-16	Buy
ApexBio Technology	B1162	FRAX597	25mg	$390	2021-12-16	Buy
Cayman Chemical	22205	FRAX597 ≥98%	1mg	$38	2024-03-01	Buy
Cayman Chemical	22205	FRAX597 ≥98%	5mg	$166	2024-03-01	Buy
Cayman Chemical	22205	FRAX597 ≥98%	10mg	$238	2024-03-01	Buy
Cayman Chemical	22205	FRAX597 ≥98%	25mg	$547	2024-03-01	Buy

Next Last

Properties

Melting point :>220°C (dec.)
storage temp. :Refrigerator
solubility :DMSO (Slightly)
form :Solid
color :Yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

p21-activated kinases (Paks) are serine/threonine protein kinases involved in cellular signaling pathways. PAK1 is an effector of Rho GTPase. PAKs are oncogenic kinases, which have been implicated as potential therapeutic targets. FRAX 597 is a PAK1 inhibitor that can reduce pancreatic cancer growth when used with Gemcitabine (G305000), an antineoplastic agent.

More related product prices

Vismodegib (GDC-0449) SB 431542 OSI-906 Bosutinib Bafetinib Thiazovivin