1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea
![1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea price.](/CAS/GIF/128831-46-9.gif)
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- $28 - $193
- Product name: 1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea
- CAS: 128831-46-9
- MF: C24H18ClF2N3O
- MW: 437.87
- EINECS:
- MDL Number:MFCD00930481
- Synonyms:1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea;N-(4-(2-chlorophenyl)-6,7-dimethyl-3-quinolyl)-N'-(2,4-difluorophenyl)urea;Urea, N-[4-(2-chlorophenyl)-6,7-dimethyl-3-quinolinyl]-N'-(2,4-difluorophenyl)-;TMP153,TMP 153
6 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
Package
- 5mg
- 10mg
- 25mg
- ManufacturerAK Scientific
- Product number8948CA
- Product descriptionN-(4-(2-Chlorophenyl)-6,7-dimethyl-3-quinolyl)-N'-(2,4-difluorophenyl)urea
- Packaging5mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8948CA
- Product descriptionN-(4-(2-Chlorophenyl)-6,7-dimethyl-3-quinolyl)-N'-(2,4-difluorophenyl)urea
- Packaging25mg
- Price$193
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000235
- Product descriptionTMP-153 95.00%
- Packaging25MG
- Price$184.8
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10010516
- Product descriptionTMP-153 ≥95%
- Packaging5mg
- Price$28
- Updated2023-01-06
- Buy
- ManufacturerCayman Chemical
- Product number10010516
- Product descriptionTMP-153 ≥95%
- Packaging10mg
- Price$50
- Updated2023-01-06
- Buy
- ManufacturerCayman Chemical
- Product number10010516
- Product descriptionTMP-153 ≥95%
- Packaging25mg
- Price$76
- Updated2023-01-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8948CA | N-(4-(2-Chlorophenyl)-6,7-dimethyl-3-quinolyl)-N'-(2,4-difluorophenyl)urea | 5mg | $133 | 2021-12-16 | Buy |
| AK Scientific | 8948CA | N-(4-(2-Chlorophenyl)-6,7-dimethyl-3-quinolyl)-N'-(2,4-difluorophenyl)urea | 25mg | $193 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000235 | TMP-153 95.00% | 25MG | $184.8 | 2021-12-16 | Buy |
| Cayman Chemical | 10010516 | TMP-153 ≥95% | 5mg | $28 | 2023-01-06 | Buy |
| Cayman Chemical | 10010516 | TMP-153 ≥95% | 10mg | $50 | 2023-01-06 | Buy |
| Cayman Chemical | 10010516 | TMP-153 ≥95% | 25mg | $76 | 2023-01-06 | Buy |
Properties
Melting point :approximate 217℃
storage temp. :Store at -20°C
solubility :DMF: 10 mg/ml,DMSO: 30 mg/ml
form :White solid.
storage temp. :Store at -20°C
solubility :DMF: 10 mg/ml,DMSO: 30 mg/ml
form :White solid.
Safety Information
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Description
TMP-153, a potent SOAT (acyl-CoA:cholesterol acyltransferase (ACAT)) inhibitor, has been shown to inhibit cholesterol esterification and reduce its influx into the plasma. In murine liver experiments, this compound has been reported to significantly reduce unesterified cholesterol content in addition to reducing the content of esterified cholesterol. Other studies have noted that TMP-153 is toxic to prion-infected neuronal (ScGT1) cells. ACAT inhibitors have demonstrated the ability to increase caspase-3 activity and prostaglandin E2 production in ScGT1 cells.Related product price
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