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ChemicalBook >> CAS DataBase List >> 4-Quinolone-3-Carboxamide CB2 Ligand

4-Quinolone-3-Carboxamide CB2 Ligand

4-Quinolone-3-Carboxamide CB2 Ligand price.
  • $36 - $761
  • Product name: 4-Quinolone-3-Carboxamide CB2 Ligand
  • CAS: 1314230-69-7
  • MF: C26H34N2O3
  • MW: 422.56
  • EINECS:
  • MDL Number:
  • Synonyms:4-Quinolone-3-Carboxamide CB2 Ligand;N-(1-adamantyl)-8-methoxy-4-oxo-1-pentylquinoline-3-carboxamide;4-Quinolone-3-Carboxamide Derivative;3-Quinolinecarboxamide, 1,4-dihydro-8-methoxy-4-oxo-1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-
8 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number6873DK
  • Product description4-Quinolone-3-CarboxamideCB2Ligand
  • Packaging25mg
  • Price$761
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3573
  • Product description4-Quinolone-3-CarboxamideCB2Ligand
  • Packaging5mg
  • Price$174
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3573
  • Product description4-Quinolone-3-CarboxamideCB2Ligand
  • Packaging10mg
  • Price$311
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3573
  • Product description4-Quinolone-3-CarboxamideCB2Ligand
  • Packaging25mg
  • Price$679
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11093
  • Product description4-Quinolone-3-Carboxamide CB2 Ligand ≥98%
  • Packaging1mg
  • Price$36
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11093
  • Product description4-Quinolone-3-Carboxamide CB2 Ligand ≥98%
  • Packaging5mg
  • Price$155
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11093
  • Product description4-Quinolone-3-Carboxamide CB2 Ligand ≥98%
  • Packaging10mg
  • Price$274
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11093
  • Product description4-Quinolone-3-Carboxamide CB2 Ligand ≥98%
  • Packaging25mg
  • Price$595
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6873DK 4-Quinolone-3-CarboxamideCB2Ligand 25mg $761 2021-12-16 Buy
ApexBio Technology C3573 4-Quinolone-3-CarboxamideCB2Ligand 5mg $174 2021-12-16 Buy
ApexBio Technology C3573 4-Quinolone-3-CarboxamideCB2Ligand 10mg $311 2021-12-16 Buy
ApexBio Technology C3573 4-Quinolone-3-CarboxamideCB2Ligand 25mg $679 2021-12-16 Buy
Cayman Chemical 11093 4-Quinolone-3-Carboxamide CB2 Ligand ≥98% 1mg $36 2024-03-01 Buy
Cayman Chemical 11093 4-Quinolone-3-Carboxamide CB2 Ligand ≥98% 5mg $155 2024-03-01 Buy
Cayman Chemical 11093 4-Quinolone-3-Carboxamide CB2 Ligand ≥98% 10mg $274 2024-03-01 Buy
Cayman Chemical 11093 4-Quinolone-3-Carboxamide CB2 Ligand ≥98% 25mg $595 2024-03-01 Buy

Properties

Boiling point :600.1±55.0 °C(Predicted)
Density :1.20±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤30mg/ml in ethanol;3mg/ml in DMSO;3mg/ml in dimethyl formamide
form :crystalline solid
pka :12.12±0.20(Predicted)

Safety Information

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Description

Cannabinoids (CBs) and their synthetic analogs produce biochemical and pharmacological effects by interacting with the central CB1 and peripheral CB2 receptors. The CB2 receptor has emerged as a pharmacotherapeutic target for treating osteoporosis, as well as for eliciting antinociceptive effects in various models of pain. 4-Quinolone-3-carboxamide CB2 ligand is a selective, high affinity ligand of the CB2 receptor, displaying a Ki value of 0.6 nM (Ki >10,000 nM for CB1) in vitro. At a dose of 6 mg/kg, 4-quinolone-3-carboxamide CB2 ligand exhibits antinociceptive activity in a formalin test of nocifensive response in mice. This analgesic affect is not significantly reversed by the CB2 antagonist AM630 , which suggests 4-quinolone-3-carboxamide CB2 ligand may behave as an inverse agonist.